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Registry of Toxic Effects of Chemical Substances (RTECS)

Phenol, 2,3,6-trichloro-

RTECS #

SN1300000

CAS #

933-75-5

Updated

December 2012

Molecular Weight

197.44

Molecular Formula

C6H3Cl3O

Synonyms

2,3,6-Trichlorophenol

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysislung/hamster200 mg/LMUREAV 241,175,1990
Cytogenetic Analysisovary/hamster400 mg/LMUREAV 303,101,1993
mutation in microorganisms/Salmonella typhimurium10 µg/plate (-enzymatic activation step)TECSDY 14,143,1987

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lethal dose (50 percent kill): 308 mg/kgBehavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold

Nutritional and Gross Metabolic: Body temperature increase
BJPCAL 13,20,1958
intraperitoneal/rat lethal dose (50 percent kill): 308 mg/kgVCVGK* -,245,1994

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/human lowest published toxic concentration: 3 mg/m3/3Y- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Other changes
VCVGK* -,247,1994

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 mg/m3, skin, MAY2011
Occupational Exposure Limit-ICELANDtime-weighted average 0.5 mg/m3, skin, NOV2011
Occupational Exposure Limit-JAPAN2B carc, MAY2012
Occupational Exposure Limit-SWEDENtime-weighted average 0.5 mg/m3;short term exposure limit 1.5 mg/m3, Skin, Carcinogen, JUN2005

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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