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Registry of Toxic Effects of Chemical Substances (RTECS)

Peroxyacetic acid

RTECS #

SD8750000

CAS #

79-21-0

Updated

July 2012

Molecular Weight

76.06

Molecular Formula

C2H4O3

Synonyms

Acetic peroxide
Acetyl hydroperoxide
Acide peracetique (French)
Desoxon 1
Estosteril
Ethaneperoxoic acid
Hydroperoxide, acetyl
Kyselina peroxyoctova (Czech)
Monoperacetic acid
Osbon AC
Peracetic acid
Peroxoacetic acid
Proxitane 4002

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 1 mg severeUCDS** 12/12/1968
skin /rabbit 500 mg open irritation test severeUCDS** 12/12/1968

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
DNA Damagemultiple/other fish0.61 mg/L/20D-continuousMUREAV 557,119,2004
DNA Damageleukocyte/human0.5 ppm/1HMUTAEX 19,157,2004
micronucleus testmultiple/other fish0.2 ppm/72H-continuousMUREAV 587,103,2005
mutation in microorganisms/Saccharomyes cerevisiae5 ppm/2HMUTAEX 19,157,2004

Tumorigenic Data and References

Route/OrganismDoseEffectReference
skin/mouse lowest published toxic dose: 21 gm/kg/26W- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Skin and Appendages: Tumors

Tumorigenic: Tumors at site of application
JNCIAM 55,1359,1975

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): 450 mg/m3GISAAA 48(6),28,1983
intravenous/mouse lethal dose (50 percent kill): 17860 µg/kgYHTPAD 23,345,1988
oral/guinea pig lethal dose (50 percent kill): 10 mg/kgBSPII* 1/75-19B
oral/mouse lethal dose (50 percent kill): 210 mg/kgGISAAA 48(6),28,1983
oral/rat lethal dose (50 percent kill): 1540 µL/kgUCDS** 12/12/1968
skin/rabbit lethal dose (50 percent kill): 1410 µL/kgUCDS** 12/12/1968
Tank with water/other fish Inhibitor Concentration Low: 1 mg/L/10DBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes
MUREAV 729,81,2012

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/guinea pig lowest published toxic concentration: 186 mg/m3/1H/90D- intermittentLiver: Fatty liver degeneration

Lung, Thorax, or Respiration: Other changes

Blood: Pigmented or nucleated red blood cells
WZHMAE 33,513,1984
inhalation/mouse lowest published toxic concentration: 186 mg/m3/1H/90D- intermittentLiver: Fatty liver degeneration

Lung, Thorax, or Respiration: Other changes
WZHMAE 33,513,1984
inhalation/rat lowest published toxic concentration: 350 mg/m3/30D- intermittentLung, Thorax, or Respiration: Other changes

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes
GISAAA 48(6),28,1983

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWMUREAV 681,80,2009

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESRED CompletedRBREV* -,331,1998
Occupational Exposure Limit-FINLANDtime-weighted average 0.2 ppm (0.6 mg/m3), short term exposure limit 0.5 ppm (1.5 mg/m3), NOV2011

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 84020; Number of Industries 2; Total Number of Facilities 31; Number of Occupations 4; Total Number of Employees Exposed 1728; Total Number of Female Employees Exposed 91
National Occupational Hazard Survey 1974Hazard Code 84020; Number of Industries 1; Total Number of Facilities 33; Number of Occupations 2; Total Number of Employees Exposed 1683

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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