Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Peroxide, bis(alpha,alpha-dimethylbenzyl)

RTECS #

SD8150000

CAS #

80-43-3

Updated

August 2008

Molecular Weight

270.40

Molecular Formula

C18H22O2

Synonyms

Active dicumyl peroxide
Bis(alpha,alpha-dimethylbenzyl)peroxide
Cumene peroxide
Cumyl peroxide
Di-alpha-cumyl peroxide
Dicumyl peroxide
Di-Cup
Di-Cup 40 KE
Di-cupr
Diisopropylbenzene peroxide
Isopropylbenzene peroxide
Luperox 500R
Luperox 500T
Peroxide, bis(1-methyl-1-phenylethyl)
Varox dcp-R
Varox dcp-T

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 5000 mg/kgVCVGK* -,536,1994
oral/mouse lethal dose (50 percent kill): 5000 mg/kgVCVGK* -,536,1994
oral/rat lethal dose (50 percent kill): 6000 mg/kgBehavioral: Somnolence (general depressed activity)

Behavioral: Food intake (animal)

Gastrointestinal: Hypermotility, diarrhea
VCVGK* -,536,1994
oral/rat lethal dose (50 percent kill): 4100 mg/kgBSPII* 1/75-19B
subcutaneous/cat lowest published toxic dose: 1000 mg/kgBlood: Methemoglobinemia- CarboxhemoglobinemiaVCVGK* -,536,1994
subcutaneous/rat lowest published toxic dose: 1000 mg/kgBlood: Methemoglobinemia- CarboxhemoglobinemiaVCVGK* -,536,1994
unreported route/rat lethal dose (50 percent kill): 3500 mg/kg34ZIAG -,655,1969

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
skin/mouse lowest published toxic dose: 216320 µg/kg/4W- intermittentBiochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammationCRNGDP 25,431,2004

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 80273; Number of Industries 11; Total Number of Facilities 606; Number of Occupations 26; Total Number of Employees Exposed 17958; Total Number of Female Employees Exposed 8122
National Occupational Hazard Survey 1974Hazard Code 80273; Number of Industries 7; Total Number of Facilities 256; Number of Occupations 25; Total Number of Employees Exposed 5641

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
TOP