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Peroxide, bis (alpha,alpha - dimethylbenzyl)

RTECS #: SD8150000

CAS #: 80-43-3


UPDATE: August 2008 MW: 270.40 MF: C18H22O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Active dicumyl peroxide
  2. Bis (alpha,alpha - dimethylbenzyl) peroxide
  3. Cumene peroxide
  4. Cumyl peroxide
  5. Di - Cup
  6. Di - Cup 40 KE
  7. Di - alpha - cumyl peroxide
  8. Di - cupr
  1. Dicumyl peroxide
  2. Diisopropylbenzene peroxide
  3. Isopropylbenzene peroxide
  4. Luperox 500R
  5. Luperox 500T
  6. Peroxide, bis (1 - methyl - 1 - phenylethyl)
  7. Varox dcp - R
  8. Varox dcp - T


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mouse
lethal dose (50 percent kill): 5,000 mg/kg N/R VCVGK* -,536,1994
oral
mouse
lethal dose (50 percent kill): 5,000 mg/kg N/R VCVGK* -,536,1994
oral
rat
lethal dose (50 percent kill): 4,100 mg/kg N/R BSPII* 1/75-19B
oral
rat
lethal dose (50 percent kill): 6,000 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Food intake (animal)

Gastrointestinal: Hypermotility, diarrhea
VCVGK* -,536,1994
subcutaneous
cat
lowest published toxic dose: 1,000 mg/kg Blood: Methemoglobinemia- Carboxhemoglobinemia VCVGK* -,536,1994
subcutaneous
rat
lowest published toxic dose: 1,000 mg/kg Blood: Methemoglobinemia- Carboxhemoglobinemia VCVGK* -,536,1994
unreported route
rat
lethal dose (50 percent kill): 3,500 mg/kg N/R 34ZIAG -,655,1969


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
skin
mouse
lowest published toxic dose: 216,320 g/kg/4 week- intermittent Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation CRNGDP 25,431,2004


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80273;
Number of Industries 7;
Total Number of Facilities 256;
Number of Occupations 25;
Total Number of Employees Exposed 5,641
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80273;
Number of Industries 11;
Total Number of Facilities 606;
Number of Occupations 26;
Total Number of Employees Exposed 17,958;
Total Number of Female Employees Exposed 8,122


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in electrical applications and as crosslinker for rubber
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
BSPII* SPI Bulletin. (Soc. of the Plastics Industry, 250 Park Ave., New York, NY 10017)
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.

Used in electrical applications and as crosslinker for rubber

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