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Registry of Toxic Effects of Chemical Substances (RTECS)

Perchloric acid, potassium salt (1:1)

RTECS #

SC9700000

CAS #

7778-74-7

Updated

October 2012

Molecular Weight

138.55

Molecular Formula

ClO4·K

Synonyms

Astrumal
Periodin
Potassium hyperchloride
Potassium perchlorate

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/rat 27675 mg/kg (1-9D pregnant)Reproductive: Specific developmental abnormalities: Endocrine systemJRPFA4 27,265,1971
oral/rabbit 2100 mg/kg (1-21D pregnant)Reproductive: Specific developmental abnormalities: Endocrine systemAMASA4 23,223,1967
oral/guinea pig 35700 mg/kg (48-68D pregnant)Reproductive: Specific developmental abnormalities: Endocrine systemENDOAO 60,53,1957

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 7980 mg/kg/19W- continuousEndocrine: Other changes

Endocrine: Changes in thymus weight
JJCREP 78,1335,1987

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWEJIME* 17,529,2006
TOXICOLOGY REVIEWENTOX* -,349,2005
TOXICOLOGY REVIEWREPTED 33,188,2012

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 80603; Number of Industries 5; Total Number of Facilities 286; Number of Occupations 8; Total Number of Employees Exposed 2640; Total Number of Female Employees Exposed 1948
National Occupational Hazard Survey 1974Hazard Code 80603; Number of Industries 2; Total Number of Facilities 142; Number of Occupations 4; Total Number of Employees Exposed 332

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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