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Perchloric acid

RTECS #: SC7500000

CAS #: 7601-90-3


UPDATE: November 2007 MW: 100.46 MF: ClHO4


NOTE:

TABLE OF CONTENTS:
  1. ACUTE TOXICITY DATA:
  2. OTHER MULTIPLE DOSE DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

N/R N/R


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
dog
lethal dose (50 percent kill): 400 mg/kg Behavioral: Excitement

Lung, Thorax, or Respiration: Dyspnea

Nutritional and Gross Metabolic: Body temperature decrease
GTPZAB 17(8),33,1973
oral
dog
lethal dose (50 percent kill): 400 mg/kg N/R ENTOX* -,352,2005
oral
rat
lethal dose (50 percent kill): 1,100 mg/kg Behavioral: Excitement

Lung, Thorax, or Respiration: Dyspnea

Nutritional and Gross Metabolic: Body temperature decrease
GTPZAB 17(8),33,1973
oral
rat
lethal dose (50 percent kill): 1,100 mg/kg N/R ENTOX* -,352,2005
subcutaneous
mouse
lethal dose (50 percent kill): 250 mg/kg Behavioral: Excitement

Lung, Thorax, or Respiration: Dyspnea

Nutritional and Gross Metabolic: Body temperature decrease
GTPZAB 17(8),33,1973
subcutaneous
mouse
lethal dose (50 percent kill): 250 mg/kg N/R ENTOX* -,352,2005


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 1.4 mg/kg/14 day- intermittent Endocrine: Evidence of thyroid hypofunction TOXID9 72,390,2003


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

TOXICOLOGY REVIEW
ENTOX* -,352,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - POLAND MAC(time-weighted average) 1 mg/m3, MAC(short term exposure limit) 3 mg/m3, JAN1999


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80182;
Number of Industries 34;
Total Number of Facilities 2,227;
Number of Occupations 13;
Total Number of Employees Exposed 7,468
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80182;
Number of Industries 27;
Total Number of Facilities 1,514;
Number of Occupations 24;
Total Number of Employees Exposed 27,220;
Total Number of Female Employees Exposed 11,531


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used for laboratory research, or fine chemical manufacturing
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-

Used for laboratory research, or fine chemical manufacturing

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