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Registry of Toxic Effects of Chemical Substances (RTECS)

Paraformaldehyde

RTECS #

RV0540000

CAS #

30525-89-4

Updated

August 2003

Molecular Weight

N/R

Molecular Formula

(CH2O)x

Synonyms

Aldacide
Flo-Mor
Formagene
Paraform

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
morphological transformembryo/rat2200 ng/plateJJATDK 1,190,1981

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): 1070 mg/m3/4HEye: Lacrimation

Lung, Thorax, or Respiration: Dyspnea

Gastrointestinal: Changes in structure or function of salivary glands
NTIS** OTS0534623
oral/rat lethal dose (50 percent kill): 800 mg/kg28ZEAL 4,308,1969

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/Dog lowest published toxic dose: 9 gm/kg/90D- continuousBehavioral: Food intake (animal)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TOLED5 30,1,1986
oral/rat lowest published toxic dose: 9 gm/kg/90D- continuousBehavioral: Fluid intake

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TOLED5 30,1,1986
oral/rat lowest published toxic dose: 365 mL/kg/2Y- continuousGastrointestinal: Other changes

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TXCYAC 56,79,1989

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEW27ZTAP 3,108,1969

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESSupportedRBREV* -,122,1998

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code M1528; Number of Industries 54; Total Number of Facilities 8271; Number of Occupations 65; Total Number of Employees Exposed 146532; Total Number of Female Employees Exposed 20414
National Occupational Hazard Survey 1974Hazard Code M1528; Number of Industries 5; Total Number of Facilities 236; Number of Occupations 19; Total Number of Employees Exposed 1872

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH CURRENT INTELLIGENCE BULLETIN #55, September 1991
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