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Palygorskite

RTECS #: RT6400000

CAS #: 12174-11-7


UPDATE: November 2007 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. TUMORIGENIC DATA:
  3. REVIEWS:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. 200U/P - Rvm
  2. Activated attapulgite
  3. Attaclay
  4. Attaclay X 250
  5. Attacote
  6. Attagel
  7. Attagel 40
  8. Attagel 50
  9. Attagel 150
  10. Attapulgite
  11. Attasorb
  1. Diluex
  2. Min - U - Gel 200
  3. Min - U - Gel 400
  4. Min - U - Gel FG
  5. Palygorskit (German)
  6. Permagel
  7. Pharmasorb - colloidal
  8. RVM - FG
  9. X 250
  10. Zeogel


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 10 mg/m3/6 hour/13 week- intermittent Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors
BJIMAG 44,749,1987
implant
rat
lowest published toxic dose: 200 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application
JJIND8 67,965,1981
intraperitoneal
rat
lowest published toxic dose: 338 mg/kg/2 week- intermittent Tumorigenic: Neoplastic by RTECS criteria

Tumorigenic: Tumors at site of application
ZHPMAT 162,467,1976


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

International Agency for Research on Cancer (IARC) Cancer Review Animal Limited Evidence IMEMDT 42,159,1987
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient (>5um) IMEMDT 68,245,1997
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 42,159,1987
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 68,245,1997
International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate (<5um) IMEMDT 68,245,1997
International Agency for Research on Cancer (IARC) Cancer Review Group 2B (fibre >5um) IMEMDT 68,245,1997
International Agency for Research on Cancer (IARC) Cancer Review Group 3 (fibre >5um) IMEMDT 68,245,1997
TOXICOLOGY REVIEW
IJTOFN 22,37,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X2204;
Number of Industries 8;
Total Number of Facilities 576;
Number of Occupations 9;
Total Number of Employees Exposed 8,199


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944-
IJTOFN International Journal of Toxicology. (Taylor & Francis, 47 Runway Rd., Suite g, Levittown, PA 19057) V.16- 1997-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ.
ZHPMAT Zentralblatt fuer Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene, Abteilung 1: Originale, Reihe B: Hygiene, Krankenhaushygiene, Betriebshygiene, Praeventive Medizin. (Stuttgart, Fed. Rep. Ger.) V.155-169, 1971-1979. For publisher information, see ZAOMDC.

Used as a mineral, natural or synthetic fiber

FDA-over the counter drug

RTECS Compound Description:
   Tumorigen
   Natural Product

ALT CAS #: 1337-76-4
ALT CAS #: 12174-28-6
ALT CAS #: 37189-50-7
ALT CAS #: 61180-55-0
ALT CAS #: 64418-16-2
ALT CAS #: 71396-54-8
ALT CAS #: 137546-91-9
Click Here for Additional Information about RTECS

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