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Octadecylamine

RTECS #: RG4150000

CAS #: 124-30-1


UPDATE: November 2006 MW: 269.58 MF: C18H39N


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 1 - Aminooctadecane
  2. 1 - Octadecylamine
  3. Adogenen 142
  4. Alamine 7
  5. Alamine 7D
  6. Amine AB
  7. Armeen 18
  8. Armeen 18D
  9. Armofilm
  10. Crodamine 1.18D
  1. Farmin 80
  2. Kemamine P990
  3. Monooctadecylamine
  4. Nissan amine AB
  5. Oktadecylamin (Czech)
  6. Stearamine
  7. Stearylamine
  8. n - Octadecylamine
  9. n - Stearylamine


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
skin
rabbit
20 mg/24 hour moderate 85JCAE -,439,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mouse
lethal dose (50 percent kill): 250 mg/kg N/R NTIS** AD691-490
oral
mouse
lethal dose (50 percent kill): 3 gm/kg Behavioral: Somnolence (general depressed activity) GISAAA 38(11),31,1973
oral
mouse
lethal dose (50 percent kill): 2,000 mg/kg N/R FEREAC 70,41726,2005
oral
rat
lethal dose (50 percent kill): 2,395 mg/kg Behavioral: Somnolence (general depressed activity) GISAAA 38(11),31,1973
oral
rat
lethal dose (50 percent kill): 2,000 mg/kg N/R FEREAC 70,41726,2005


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intramuscular
dog
lowest published toxic dose: 5,475 mg/kg/1 year- continuous Gastrointestinal: Gastritis

Gastrointestinal: Other changes
EPASR* #40-8484004,2000
intramuscular
rat
lowest published toxic dose: 31,350 mg/kg/209 day- continuous Gastrointestinal: Gastritis

Gastrointestinal: Other changes
EPASR* #40-8484004,2000
oral
dog
lowest published toxic dose: 5,475 mg/kg/1 year- intermittent Nutritional and Gross Metabolic: Weight loss or decreased weight gain FEREAC 70,41726,2005
oral
rat
lowest published toxic dose: 313 gm/kg/30 week- continuous Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field JACTDZ 14,196,1995
oral
rat
lowest published toxic dose: 109,500 mg/kg/2 year- continuous Gastrointestinal: Other changes

Liver: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
FEREAC 70,41726,2005


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83376;
Number of Industries 9;
Total Number of Facilities 166;
Number of Occupations 9;
Total Number of Employees Exposed 1,676
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83376;
Number of Industries 13;
Total Number of Facilities 634;
Number of Occupations 11;
Total Number of Employees Exposed 4,674;
Total Number of Female Employees Exposed 363


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

NIOSH PROFILE (AMINES, PRIMARY ALIPHATIC), SRI, 2/77

RTECS Compound Description:
   Agricultural Chemical
   Primary Irritant

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