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Registry of Toxic Effects of Chemical Substances (RTECS)

Octadecylamine

RTECS #

RG4150000

CAS #

124-30-1

Updated

November 2006

Molecular Weight

269.58

Molecular Formula

C18H39N

Synonyms

1-Aminooctadecane
1-Octadecylamine
Adogenen 142
Alamine 7
Alamine 7D
Amine AB
Armeen 18
Armeen 18D
Armofilm
Crodamine 1.18D
Farmin 80
Kemamine P990
Monooctadecylamine
Nissan amine AB
n-Octadecylamine
n-Stearylamine
Oktadecylamin (Czech)
Stearamine
Stearylamine

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /rabbit 20 mg/24H moderate85JCAE -,439,1986

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 250 mg/kgNTIS** AD691-490
oral/mouse lethal dose (50 percent kill): 3 gm/kgBehavioral: Somnolence (general depressed activity)GISAAA 38(11),31,1973
oral/mouse lethal dose (50 percent kill): 2000 mg/kgFEREAC 70,41726,2005
oral/rat lethal dose (50 percent kill): 2395 mg/kgBehavioral: Somnolence (general depressed activity)GISAAA 38(11),31,1973
oral/rat lethal dose (50 percent kill): 2000 mg/kgFEREAC 70,41726,2005

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
intramuscular/Dog lowest published toxic dose: 5475 mg/kg/1Y- continuousGastrointestinal: Gastritis

Gastrointestinal: Other changes
EPASR* #40-8484004,2000
intramuscular/rat lowest published toxic dose: 31350 mg/kg/209D- continuousGastrointestinal: Gastritis

Gastrointestinal: Other changes
EPASR* #40-8484004,2000
oral/Dog lowest published toxic dose: 5475 mg/kg/1Y- intermittentNutritional and Gross Metabolic: Weight loss or decreased weight gainFEREAC 70,41726,2005
oral/rat lowest published toxic dose: 313 gm/kg/30W- continuousRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldJACTDZ 14,196,1995
oral/rat lowest published toxic dose: 109500 mg/kg/2Y- continuousGastrointestinal: Other changes

Liver: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
FEREAC 70,41726,2005

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 83376; Number of Industries 13; Total Number of Facilities 634; Number of Occupations 11; Total Number of Employees Exposed 4674; Total Number of Female Employees Exposed 363
National Occupational Hazard Survey 1974Hazard Code 83376; Number of Industries 9; Total Number of Facilities 166; Number of Occupations 9; Total Number of Employees Exposed 1676

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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