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Registry of Toxic Effects of Chemical Substances (RTECS)

1-Octadecanol

RTECS #

RG2010000

CAS #

112-92-5

Updated

October 2011

Molecular Weight

270.56

Molecular Formula

C18H38O

Synonyms

Adol 68
Alfol 18
Atalco S
CO-1895
CO-1897
Crodacol-S
Decyl octyl alcohol
Dytol E-46
Lanette 18
Lorol 28
n-Octadecanol
n-Octadecyl alcohol
Octadecanol
Octadecyl alcohol
Polaax
Sipol S
Siponol S
Stearol
Stearyl alcohol
Steraffine
USP XIII stearyl alcohol

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg/24H mildJACTDZ 4(5),1,1985
skin /human 30%CODEDG 57,58,2007
skin /man 30%/2D mildCODEDG 60,295,2009
skin /rabbit 500 mg/24H mildJACTDZ 4(5),1,1985

Tumorigenic Data and References

Route/OrganismDoseEffectReference
implant/mouse lowest published toxic dose: 1000 mg/kgTumorigenic: Neoplastic by RTECS criteria

Kidney, Ureter, and Bladder: Bladder tumors
CNREA8 26,105,1966

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/rat lethal dose (50 percent kill): >5000 mg/kgBehavioral: Somnolence (general depressed activity)HPV112 -,-,2008
oral/rat lethal dose (50 percent kill): >7960 mg/kgGastrointestinal: Hypermotility, diarrheaHPV112 -,-,2008
oral/rat lethal dose (50 percent kill): >2000 mg/kgHPV112 -,-,2008
skin/mammal (species unspecified) lethal dose (50 percent kill): >2000 mg/kgHPV112 -,-,2008

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 80705; Number of Industries 177; Total Number of Facilities 22262; Number of Occupations 127; Total Number of Employees Exposed 508141; Total Number of Female Employees Exposed 181509
National Occupational Hazard Survey 1974Hazard Code 80705; Number of Industries 37; Total Number of Facilities 3948; Number of Occupations 44; Total Number of Employees Exposed 60590

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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