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Registry of Toxic Effects of Chemical Substances (RTECS)

Nitric acid, cobalt(2+) salt, hexahydrate

RTECS #

QU7355500

CAS #

10026-22-9

Updated

September 201

Molecular Weight

291.07

Molecular Formula

CoN2O6·6H2O

Synonyms

Cobalt dinitrate hexahydrate
Cobalt nitrate hexahydrate
Cobalt(2+) nitrate hexahydrate
Cobalt(II) nitrate hexahydrate
Cobaltous nitrate hexahydrate

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lowest published lethal dose: 250 mg/kgBehavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Respiratory depression
JAPMA8 47,285,1958
oral/rat lethal dose (50 percent kill): 691 mg/kgBehavioral: Somnolence (general depressed activity)

Gastrointestinal: Hypermotility, diarrhea

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
FCTOD7 20,311,1982
subcutaneous/mouse lethal dose (50 percent kill): 171 mg/kgAPTOA6 9,259,1953

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.02 mg(Co)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Confirmed animal carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 52,363,1991
International Agency for Research on Cancer (IARC)Cancer Review:Group 2BIMEMDT 52,363,1991

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-HUNGARYtime-weighted average 0.1 mg(Co)/m3, short term exposure limit 0.4 mg(Co)/m3, SEP2000
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.05 mg(Co)/m3, 2B carc, a1 sen, s2 sen, MAY2012
Occupational Exposure Limit-SWEDENtime-weighted average 0.05 mg(Co)/m3, Sen, JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.05 mg(Co)/m3, carc 2, inhal, skin, sen, JAN2011
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.1 mg(Co)/m3, sen, OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO COBALT METAL, dust and fume-air10H time-weighted average 0.05 mg/m3NIOSH* DHHS #92-100,1992
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