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2 - Naphthoic acid, 3 - hydroxy -

RTECS #: QL1755000

CAS #: 92-70-6

UPDATE: September 1998 MW: 188.19 MF: C11H8O3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. 2 - Naphthalenecarboxylic acid, 3 - hydroxy - (9CI)
  2. 3 - Hydroxy - 2 - naphthalenecarboxylic acid
  3. 3 - Hydroxy - 2 - naphthoic acid
  4. BON
  5. BON acid
  6. BONA
  7. C.I. Developer 8
  1. C.I. Developer 20 (Obs.)
  2. Developer BON
  3. Kyselina 3 - hydroxy - 2 - naftoova (Czech)
  4. Miketazol Developer ONS
  5. Naphthol B.O.N.
  6. beta - Hydroxynaphthoic acid


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
guinea pig 		lowest published lethal dose: 200 mg/kg N/R NTIS** OTS0533574
intraperitoneal
mouse 		lethal dose (50 percent kill): 100 mg/kg Behavioral: General anesthetic

Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia 		NTIS** OTS0533574
intraperitoneal
rat 		lowest published lethal dose: 100 mg/kg N/R NTIS** OTS0533574
oral
guinea pig 		lowest published lethal dose: 783 mg/kg N/R NTIS** OTS0533574
oral
mouse 		lethal dose (50 percent kill): 800 mg/kg N/R 85JCAE -,663,1986
oral
rat 		lethal dose (50 percent kill): 832 mg/kg N/R NTIS** OTS0533749
subcutaneous
rat 		lowest published lethal dose: 376 mg/kg N/R AIPTAK 176,193,1968


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 8,400 mg/kg/28 day- intermittent Liver: Changes in liver weight

Endocrine: Other changes

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) 		NTIS** OTS0590059


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83636;
Number of Industries 3;
Total Number of Facilities 49;
Number of Occupations 4;
Total Number of Employees Exposed 1,414
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83636;
Number of Industries 2;
Total Number of Facilities 27;
Number of Occupations 17;
Total Number of Employees Exposed 1,639


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

RTECS Compound Description:
   Drug

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