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Registry of Toxic Effects of Chemical Substances (RTECS)

Naphthenic acid

RTECS #

QK8750000

CAS #

1338-24-5

Updated

April 2010

Molecular Weight

N/R

Molecular Formula

N/R

Synonyms

Agenap
Naphid
Sunaptic acid B
Sunaptic acid C

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 0.1 mLHPV367 -,-,2003

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lethal dose (50 percent kill): 640 mg/kgBehavioral: Food intake (animal)

Gastrointestinal: Peritonitis
AMIHAB 12,477,1955
oral/mouse lethal dose (50 percent kill): 3550 mg/kgBehavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Respiratory depression

Gastrointestinal: Hypermotility, diarrhea
HPV367 -,-,2003
oral/rat lethal dose (50 percent kill): 5.88 gm/kgBehavioral: Tremor

Cardiac: Cardiomegaly

Gastrointestinal: Other changes
HPV367 -,-,2003
oral/rat lethal dose (50 percent kill): 3 gm/kgBehavioral: Food intake (animal)

Gastrointestinal: Hypermotility, diarrhea

Gastrointestinal: Other changes
AMIHAB 12,477,1955
skin/rabbit lethal dose (50 percent kill): >3.16 gm/kgBehavioral: Somnolence (general depressed activity)

Behavioral: Food intake (animal)

Gastrointestinal: Hypermotility, diarrhea
HPV367 -,-,2003

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 5400 mg/kg/90D- continuousBrain and Coverings: Changes in brain weight

Liver: Changes in liver weight

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
HPV367 -,,2003
oral/rat lowest published toxic dose: 30000 mg/kg/30D- continuousBehavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Respiratory depression

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
HPV367 -,,2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 81676; Number of Industries 50; Total Number of Facilities 3339; Number of Occupations 52; Total Number of Employees Exposed 61935; Total Number of Female Employees Exposed 5519
National Occupational Hazard Survey 1974Hazard Code 81676; Number of Industries 43; Total Number of Facilities 2827; Number of Occupations 46; Total Number of Employees Exposed 30254

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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