Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Naphthalene, 1-methyl-

RTECS #

QJ9630000

CAS #

90-12-0

Updated

September 201

Molecular Weight

142.21

Molecular Formula

C11H10

Synonyms

1-Methylnaphthalene
alpha-Methylnaphthalene

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /rabbit 0.05 mL/24H moderateETOPFR 16,153,2004

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium6 mmol/L/2H (-enzymatic activation step)CNREA8 39,4152,1979
sister chromatid exchangelymphocyte/human250 µmol/LMUREAV 208,155,1988

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lethal dose (50 percent kill): 1.84 gm/kgBehavioral: Ataxia

Lung, Thorax, or Respiration: Respiratory depression

Nutritional and Gross Metabolic: Body temperature decrease
VCVGH* -,227,1990
oral/rat lethal dose (50 percent kill): 1840 mg/kg85GMAT -,85,1982
skin/rabbit lowest published lethal dose: 7500 mg/kgNTIS** OTS0556357
skin/rabbit lowest published toxic dose: 0.03 mL/kg/24HVascular: Measurement of regional blood flowETOPFR 16,153,2004

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 15 gm/kg/2W- intermittentNutritional and Gross Metabolic: Weight loss or decreased weight gainNTIS** OTS0556357

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.5 ppm (skin)DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWMUREAV 636,95,2007
TOXICOLOGY REVIEWTXCYAC 260,16,2009

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 20 mg/m3, JUN2003

Status in Federal Agencies

OrganizationReference
ATSDR TOXICOLOGY PROFILE (NTIS** PB/95/264362)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
TOP