CDC logo, Safer Healthier People  CDC HomeCDC SearchCDC Health Topics A-Z
NIOSH - National Institute for Occupational Safety and Health

Search NIOSH  |  NIOSH Home  |  NIOSH Topics  |  Site Index  |  Databases and Information Resources  |  NIOSH Products  |  Contact Us






Mercury, (acetato) phenyl -

RTECS #: OV6475000

CAS #: 62-38-4


UPDATE: May 2009 MW: 336.75 MF: C8H8HgO2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. REPRODUCTIVE EFFECTS DATA:
  5. ACUTE TOXICITY DATA:
  6. OTHER MULTIPLE DOSE DATA:
  7. REVIEWS:
  8. STANDARDS AND REGULATIONS:
  9. NIOSH DOCUMENTATION AND SURVEILLANCE:
  10. STATUS IN FEDERAL AGENCIES:
  11. REFERENCES:

SYNONYMS:

  1. (Acetato) phenylmercury
  2. (Acetoxymercuri) benzene
  3. Acetate phenylmercurique (French)
  4. Acetic acid, phenylmercury deriv.
  5. Acetoxyphenylmercury
  6. Algimycin 200
  7. Anticon
  8. Antimucin WBR
  9. Antimucin WDR
  10. Benzene, (acetoxymercuri) -
  11. Bufen
  12. Bufen 30
  13. Ceresol
  14. Contra Creme
  15. Dyanacide
  16. Femma
  17. Fenylmerkuriacetat (Czech)
  18. Fungicide R
  19. Fungitox OR
  20. Hexasan
  21. Hexasan (fungicide)
  22. Intercide 60
  23. Intercide PMA 18
  24. Liquiphene
  25. Lorophyn
  26. Mercuriphenyl acetate
  27. Mercuron
  28. Mercury (II) acetate, phenyl -
  29. Mercury, acetoxyphenyl -
  30. Mergal A 25
  31. Mersolite D
  32. Mersolite 8
  33. Neantina
  34. Norforms
  35. Nuodex PMA 18
  36. Nylmerate
  37. Octan fenylrtutnaty (Czech)
  38. PMA (fungicide)
  1. PMAC
  2. PMAS
  3. Panomatic
  4. Phenomercuric acetate
  5. Phenyl mercuric acetate
  6. Phenylmercuriacetate
  7. Phenylmercury acetate
  8. Phenylmercury (II) acetate
  9. Phenylquecksilberacetat (German)
  10. Phix
  11. Programin
  12. Purasan - SC - 10
  13. Puraturf 10
  14. Quicksan
  15. Quicksan 20
  16. RCRA waste number P092
  17. Ruberon
  18. Samtol
  19. Sanitized SPG
  20. Scutl
  21. Seed Dressing R
  22. Seedtox
  23. Setrete
  24. Shimmerex
  25. Spor - Kil
  26. Spruce Seal
  27. Tag
  28. Tag 331
  29. Tag HL 331
  30. Tag fungicide
  31. Trigosan
  32. Troysan 30
  33. Troysan PMA 30
  34. Verdasan
  35. Volpar
  36. Zaprawa Nasienna R
  37. Ziarnik


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
50 g/24 hour severe 85JCAE -,1205,1986
skin
human
100 g/24 hour severe ARDEAC 106,129,1972


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
cytogenetic analysis oral
pig
160 mg/kg/32 day- continuous VETNAL 52(8),91,1975
DNA inhibition mouse lymphocyte 1 mol/L BCPCA6 24,489,1975
DNA repair Bacillus subtilis 50 mmol/L MUREAV 31,185,1975
DNA repair Bacillus subtilis 1 mmol/L MUREAV 77,109,1980
DNA repair Escherichia coli 2 mmol/L MJDHDW 28,F39,1980
other mutation test systems mouse lymphocyte 10 mol/L BCPCA6 24,489,1975
sister chromatid exchange human lymphocyte 30 mg/L DBABEF 8,105,1984
sex chromosome loss and nondisjunction oral
Drosophila melanogaster
200 ppm ENVRAL 36,218,1985


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mammal (species unspecified)
lowest published toxic dose: 125 g/kg (8 day pregnant) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants) TXCYAC 6,281,1976
intravaginal
mouse
lowest published toxic dose: 110 g/kg (7 day pregnant) Reproductive: Effects on embryo or fetus: Fetal death

Reproductive: Specific developmental abnormalities: Musculoskeletal system
ARINAU 3,88,1956
intravenous
hamster
lowest published toxic dose: 7,500 g/kg (8 day pregnant) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Homeostasis
LSBGAY 10,1341,1971
intravenous
hamster
lowest published toxic dose: 8 mg/kg (8 day pregnant) Reproductive: Specific developmental abnormalities: Central nervous system LSBGAY 10,1341,1971
oral
hamster
lowest published toxic dose: 20 mg/kg (5 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) PARWAC 22,263,1980
oral
rat
lowest published toxic dose: 15 mg/kg (6-10 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Homeostasis

Reproductive: Other developmental abnormalities
PARWAC 22,263,1980
oral
rabbit
lowest published toxic dose: 9 mg/kg (8-12 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Homeostasis

Reproductive: Other developmental abnormalities
PARWAC 22,263,1980
subcutaneous
mouse
lowest published toxic dose: 110 g/kg (8 day pregnant) Reproductive: Effects on embryo or fetus: Fetal death ARINAU 3,88,1956


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mammal (species unspecified)
lethal dose (50 percent kill): 10 mg/kg N/R TXCYAC 6,281,1976
intraperitoneal
mouse
lethal dose (50 percent kill): 13 mg/kg N/R AMSVAZ 143,365,1952
intravenous
mouse
lethal dose (50 percent kill): 18 mg/kg N/R CSLNX* NX#00921
oral
chicken
lethal dose (50 percent kill): 60 mg/kg N/R TXAPA9 2,344,1960
oral
mouse
lethal dose (50 percent kill): 13,250 g/kg N/R YAKUD5 22,291,1980
oral
quail
lethal dose (50 percent kill): 71 mg/kg N/R AXVMAW 34,383,1980
oral
rat
lethal dose (50 percent kill): 41 mg/kg N/R ATDAEI 1,175,1992
subcutaneous
mouse
lethal dose (50 percent kill): 12 mg/kg N/R TOIZAG 9,101,1962
unreported route
mammal (species unspecified)
lethal dose (50 percent kill): 17 mg/kg N/R 30ZDA9 -,295,1971


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 91 mg/kg/13 week- continuous Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes
ATSUDG 4,201,1980
oral
rat
lowest published toxic dose: 346 mg/kg/1 year- continuous Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) AMIHBC 2,433,1950
oral
rat
lowest published toxic dose: 5,840 mg/kg/2 year- continuous Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
HBPTO* 2,1380,2001
oral
rat
lowest published toxic dose: 456.25 mg/kg/2 year- continuous Kidney, Ureter, and Bladder: Other changes HBPTO* 2,1380,2001
skin
human
lowest published toxic concentration: 0.5 pph/48 hour- continuous Skin: After topical application: Dermatitis, allergic AJCDE* 13,3,2002


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 58,239,1993
International Agency for Research on Cancer (IARC) Cancer Review Group 2B IMEMDT 58,239,1993
TOXICOLOGY REVIEW
AJOGAH 126,390,1976
TOXICOLOGY REVIEW
SDGTB3 1,177,1971
TOXICOLOGY REVIEW
BIOGAL 41(7),208,1975
TOXICOLOGY REVIEW
ADTEAS 5,51,1972
TOXICOLOGY REVIEW
JTEHD6 7,267,2004
TOXICOLOGY REVIEW
HTOPA* 1,701,2002


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,199,1998
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.05 mg(Hg)/m3 DTLWS* 3,22,1973
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.1 mg(Hg)/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.1 mg(Hg)/m3, Skin, MAR2002
Occupational Exposure Limit - FINLAND time-weighted average 1 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 0.1 mg(Hg)/m3, Skin, FEB2006
Occupational Exposure Limit - HUNGARY time-weighted average 0.01 mg(Hg)/m3, short term exposure limit 0.04 mg(Hg)/m3, Skin, SEP2000
Occupational Exposure Limit - NORWAY time-weighted average 0.05 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.05 mg(Hg)/m3, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.05 mg(Hg)/m3, MAC(short term exposure limit) 0.15 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 0.05 mg(Hg)/m3, short term exposure limit 0.2 mg(Hg)/m3, Skin, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 0.01 mg(Hg)/m3, Skin, JUN2005
Occupational Exposure Limit - THAILAND short term exposure limit 0.05 mg(Hg)/m3, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO MERCURY, ARYL AND INORGANIC-air ceiling concentration 0.1 mg/m3 (Sk) NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 57340;
Number of Industries 11;
Total Number of Facilities 588;
Number of Occupations 29;
Total Number of Employees Exposed 10,962
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 57340;
Number of Industries 27;
Total Number of Facilities 2,429;
Number of Occupations 30;
Total Number of Employees Exposed 28,342;
Total Number of Female Employees Exposed 5,150


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA GENETOX PROGRAM 1988, Positive: D melanogaster-whole sex chrom. loss
EPA GENETOX PROGRAM 1988, Positive: D melanogaster-nondisjunction; B subtilis rec assay
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used for fungal and bacterial control and control of crabgrass
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72. Discontinued.
AJCDE* American Journal of Contact Dermatitis: Official Journal of the American Contact Dermatitis Society (Philadelphia, PA : W.B. Saunders, Harcourt Brace Jovanovich) V.1-14 1990-2003.
AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920-
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
AMSVAZ Acta Medica Scandinavica. (Almqvist & Wiksell, POB 45150, S-10430 Stockholm, Sweden) V.52-224, 1919-88.
ARDEAC Archives of Dermatology. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.82- 1960-
ARINAU Annual Report of the Research Institute of Environmental Medicine, Nagoya University. (Nagoya, Japan) V.1-25, 1951-80.
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990-
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978-
AXVMAW Archiv fuer Experimentelle Veterinaermedizin. (S. Hirzel Verlag, Postfach 506, Leipzig DDR-7010, Ger. Dem. Rep.) V.6- 1952-
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958-
BIOGAL Biologico. (Instituto Biologica, Av. Cons. Rodriques Alves, 1252, CEP 04014, Sao Paulo, Brazil) V.1- 1935-
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
DBABEF Doga Bilim Dergisi, Seri A2: Biyoloji. Natural Science Journal, Series A2. (Turkiye Bilimsel ve Teknik Arastirma Kurumu, Ataturk Bul. No. 221, Kavaklidere, Ankara, Turkey) V.8- 1984-
DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8.
ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
HBPTO* Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
HTOPA*
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
LSBGAY Life Sciences, Part 2: Biochemistry, General and Molecular Biology. (New York, NY) V.9-13, 1970-73. For publisher information, see LIFSAK.
MJDHDW Mukogawa Joshi Daigaku Kiyo, Shokumotsu-hen. Bulletin of Mukogawa Women's University, Food Science Series. (Mukogawa Joshi Daigaku, 6-46, Ikebiraki-cho, Nishinomiya, Hyogo-ken, Japan) No.19- 1972-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
PARWAC Polskie Archiwum Weterynaryjne. Polish Archives of Veterinary Medicine. (Panstwowe Wydawnictwo Naukowe, POB 391, 00251 Warsaw, Poland) V.1- 1951-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
SDGTB3 Seminars in Drug Treatment. (New York, NY) V.1-3, 1971-74. Discontinued.
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924-
YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959-

Used for fungal and bacterial control and control of crabgrass

NIOSH PROFILE (ORGANIC MERCURY), SRC, 10/77

RTECS Compound Description:
   Agricultural Chemical
   Tumorigen
   Organometallic
   Mutagen
   Reproductive Effector
   Human Data
   Primary Irritant

ALT CAS #: 1337-06-0
ALT CAS #: 61840-45-7
ALT CAS #: 64684-45-3
Click Here for Additional Information about RTECS

NIOSH Home |  NIOSH Search  |  Site Index  |  Topic List |  Contact Us