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Registry of Toxic Effects of Chemical Substances (RTECS)

Lead tetroxide

RTECS #

OG5425000

CAS #

1314-41-6

Updated

September 201

Molecular Weight

685.57

Molecular Formula

O4Pb3

Synonyms

C.I. 77578
C.I. Pigment Red 105
Gold satinobre
Heuconin 5
Lead orthoplumbate
Lead oxide (3:4)
Lead oxide (Pb3O4)
Lead Oxide Red
Lead tetraoxide
Mennige
Mineral Orange
Mineral Red
Minium
Minium Non-Setting RL 95
Orange Lead
Paris Red
Pigment Red 105
Plumboplumbic oxide
Red Lead
Red Lead Oxide
Sandix
Saturn Red
Trilead tetraoxide
Trilead tetroxide

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/guinea pig lethal dose (50 percent kill): 220 mg/kg85KYAH 11,854,1989
intraperitoneal/mouse lethal dose (50 percent kill): 17700 mg/kgGTPZAB 26(8),51,1982
intraperitoneal/rat lethal dose (50 percent kill): 630 mg/kgGTPZAB 19(3),30,1975
oral/guinea pig lowest published lethal dose: 1 gm/kgBehavioral: Convulsions or effect on seizure threshold

Blood: Pigmented or nucleated red blood cells
AHBAAM 125,273,1941

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.05 mg(Pb)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Confirmed animal carcinogenDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEW85DHAX Pb,254,1972

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-ARAB Republic of Egypttime-weighted average 0.05 mg(Pb)/m3, JAN1993
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.15 mg(Pb)/m3 (dust, fume), JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.15 mg(Pb)/m3 (dust, fume), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.05 mg(Pb)/m3 (fume, dust), MAY2011
Occupational Exposure Limit-FRANCEVME 0.1 mg(Pb)/m3, FEB2006
Occupational Exposure Limit-HUNGARYtime-weighted average 0.05 mg(Pb)/m3, short term exposure limit 0.2 mg(Pb)/m3 (resp), SEP2000
Occupational Exposure Limit-HUNGARYtime-weighted average 0.15 mg(Pb)/m3, short term exposure limit 0.6 mg(Pb)/m3, SEP2000
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.1 mg(Pb)/m3, 2B carc, MAY2012
Occupational Exposure Limit-MEXICOtime-weighted average 0.15 mg(Pb)/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.1 mg(Pb)/m3 (dust and fume), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.05 mg(Pb)/m3, JAN1999
Occupational Exposure Limit-POLANDMAC(time-weighted average) 0.05 mg(Pb)/m3, JAN1999
Occupational Exposure Limit-RUSSIAtime-weighted average 0.05 mg(Pb)/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 0.1 mg(Pb)/m3 (total dust);time-weighted average 0.5 mg(Pb)/m3 (resp. dust), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.1 mg(Pb)/m3, KZG-week 0.8 mg(Pb)/m3, carc 3, inhal, JAN2011
Occupational Exposure Limit-THAILANDtime-weighted average 0.2 mg(Pb)/m3, JAN1993
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.15 mg(Pb)/m3, JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 0.2 mg(Pb)/m3, JAN1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO LEAD, INORGANIC-air10H time-weighted average <0.1 mg(Pb)/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code M0126; Number of Industries 20; Total Number of Facilities 1687; Number of Occupations 23; Total Number of Employees Exposed 18022; Total Number of Female Employees Exposed 1630
National Occupational Hazard Survey 1974Hazard Code M0126; Number of Industries 41; Total Number of Facilities 2103; Number of Occupations 36; Total Number of Employees Exposed 28875

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NTP 11th Report on Carcinogens,2004:Reasonably anticipated to be a human carcinogen
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