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Registry of Toxic Effects of Chemical Substances (RTECS)

Lauroyl peroxide

RTECS #

OF2625000

CAS #

105-74-8

Updated

November 2003

Molecular Weight

398.70

Molecular Formula

C24H46O4

Synonyms

Alperox C
Dilauroyl peroxide
Dilauryl peroxide
Dodecanoyl peroxide
Dyp-97F
Laurox
Laurydol
LYP 97
LYP 97F
Peroxide, bis(1-oxododecyl)-
Peroxyde de lauroyle (French)

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 500 mg/24H mild85JCAE -,324,1986
skin /mouse 20 mg mildVCVGK* -,541,1994

Tumorigenic Data and References

Route/OrganismDoseEffectReference
subcutaneous/mouse lowest published toxic dose: 184 mg/kg/46W- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application
JNCIAM 37,825,1966
unreported route/mouse lowest published toxic dose: 638 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Blood: Lymphoma including Hodgkin's disease
RARSAM 3,193,1963

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/rat lethal dose (50 percent kill): 10000 mg/kgCardiac: Other changes

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes
VCVGK* -,541,1994

Reviews

OrganizationStandardReference
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 36,315,1985
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 71,1485,1999
International Agency for Research on Cancer (IARC)Cancer Review:Human No Adequate DataIMEMDT 36,315,1985
International Agency for Research on Cancer (IARC)Cancer Review:Human No Adequate DataIMEMDT 71,1485,1999
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMEMDT 71,1485,1999

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 83575; Number of Industries 1; Total Number of Facilities 60; Number of Occupations 3; Total Number of Employees Exposed 3960
National Occupational Hazard Survey 1974Hazard Code 83575; Number of Industries 1; Total Number of Facilities 28; Number of Occupations 6; Total Number of Employees Exposed 532

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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