Hydrobromic acid

RTECS #
MW3850000
CAS #
10035-10-6
See: NMAM or OSHA Methods
Updated
October 2015
Molecular Weight
80.92
Molecular Formula
BrH
Synonyms
Acide bromhydrique (French)
Acido bromidrico (Italian)
Anhydrous hydrobromic acid
Bromowodor (Polish)
Bromwasserstoff (German)
Broomwaterstof (Dutch)
Hydrogen bromide
Hydrogen bromide (ACGIH:OSHA)

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
In Vitro/Human, skin Inhibitor Concentration Low: 48 pph/3MIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 28,616,2014
inhalation/mouse lethal concentration (50 percent kill): 814 ppm/1HENTOX* -,537,2005
inhalation/rat lowest published toxic concentration: 10 mg/m3/4HLung, Thorax, or Respiration: Other changesTPKVAL 14,73,1975
inhalation/rat lowest published toxic concentration: 26 mg/m3Olfaction: Change in sensation of smell

Lung, Thorax, or Respiration: Dyspnea
VCVN5* -,393,1989
inhalation/rat lethal concentration (50 percent kill): 3000 ppm/30MENTOX* -,639,2005
inhalation/rat lethal concentration (50 percent kill): 2858 ppm/1HENTOX* -,537,2005
intraperitoneal/rat lethal dose (50 percent kill): 76 mg/kgGISAAA 41(1),105,1976

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-ceiling concentration 2 ppmDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWENTOX* -,639,2005
TOXICOLOGY REVIEWENTOX* -,537,2005

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 3 ppm (10 mg/m3)DTLVS* 3,128,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAceiling concentration 3 ppm (9.9 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 2 ppm (6.7 mg/m3);KZW 2 ppm (6.7 mg/m3), 2007
Occupational Exposure Limit-BELGIUMshort term exposure limit 2 ppm (6.7 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKceiling concentration 2 ppm (6.7 mg/m3), MAY2011
Occupational Exposure Limit-ECshort term exposure limit 6.7 mg/m3 (2 ppm), JUN2000
Occupational Exposure Limit-FINLANDshort term exposure limit 2 ppm (6.7 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVLE 2 ppm (6.7 mg/m3), FEB2006
Occupational Exposure Limit-GERMANYMAK 2 ppm (6.7 mg/m3), 2011
Occupational Exposure Limit-HUNGARYshort term exposure limit 6.7 mg/m3, SEP2000
Occupational Exposure Limit-ICELANDshort term exposure limit 2 ppm (6.7 mg/m3), NOV2011
Occupational Exposure Limit-KOREAceiling concentration 3 ppm (10 mg/m3), 2006
Occupational Exposure Limit-MEXICOpeak 3 ppm (10 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDceiling concentration 3 ppm (9.9 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 3 ppm (10 mg/m3), JAN1999
Occupational Exposure Limit-PERUshort term exposure limit 3 ppm (10 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 7 mg/m3, MAC(short term exposure limit) 21 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAshort term exposure limit 2 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 1 ppm (3.5 mg/m3), ceiling concentration 2 ppm (7 mg/m3), JUN2005
Occupational Exposure Limit-SWITZERLANDceiling concentration 2 ppm (6.7 mg/m3), JAN2011
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 3 ppm (10 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 5 ppm (17 mg/m3), JAN1993
Occupational Exposure Limit-UNITED KINGDOMshort term exposure limit 3 ppm (10 mg/m3), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 3 ppm (10 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 3 ppm (10 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 3 ppm (10 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 3 ppm (10 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO HYDROGEN BROMIDE-airceiling concentration 3 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 38575; Number of Industries 23; Total Number of Facilities 1103; Number of Occupations 26; Total Number of Employees Exposed 20571; Total Number of Female Employees Exposed 5398
National Occupational Hazard Survey 1974Hazard Code 38575; Number of Industries 13; Total Number of Facilities 510; Number of Occupations 12; Total Number of Employees Exposed 2643

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Acids, inorganic, 7903
Page last reviewed: November 16, 2018