Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

1,6-Hexanediol

RTECS #

MO2100000

CAS #

629-11-8

Updated

August 2006

Molecular Weight

118.20

Molecular Formula

C6H14O2

Synonyms

1,6-Dihydroxyhexane
alpha,omega-Hexanediol
HDO
Hexamethylene glycol
Hexamethylenediol
omega-Hexanediol

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mgIHFCAY 6,1,1967
eye /rabbit 500 mg/24H mild85JCAE -,210,1986
skin /rabbit 500 mg/24H mild85JCAE -,210,1986

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 1738 mg/kgTXAPA9 49,385,1979
intraperitoneal/rat lowest published toxic dose: 1350 mg/kgBehavioral: AtaxiaVCVGK* -,155,1984
oral/mouse lethal dose (50 percent kill): 2400 mg/kgGastrointestinal: Other changesVCVGK* -,155,1984
oral/rat lethal dose (50 percent kill): 3700 mg/kgGastrointestinal: Other changesVCVGK* -,155,1984
oral/rat lethal dose (50 percent kill): 3730 mg/kgTXAPA9 28,313,1974
skin/rabbit lethal dose (50 percent kill): >10 gm/kgTXAPA9 28,313,1974

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 10764 mg/kg/26D- intermittentNutritional and Gross Metabolic: Weight loss or decreased weight gainNRTXDN 26,229,2005

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 83598; Number of Industries 3; Total Number of Facilities 59; Number of Occupations 11; Total Number of Employees Exposed 3529; Total Number of Female Employees Exposed 313
National Occupational Hazard Survey 1974Hazard Code 83598; Number of Industries 2; Total Number of Facilities 36; Number of Occupations 6; Total Number of Employees Exposed 1740

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
TOP