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Hexanal, 2 - ethyl -

RTECS #: MN7525000

CAS #: 123-05-7


UPDATE: February 2006 MW: 128.24 MF: C8H16O


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STANDARDS AND REGULATIONS:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 2 - Ethylhexaldehyde
  2. 2 - Ethylhexanal
  3. Butyl ethyl acetaldehyde
  4. Ethylbutylacetaldehyde
  1. Ethylhexaldehyde
  2. alpha - Ethylcaproaldehyde
  3. beta - Propyl - alpha - ethylacrolein


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
skin
rabbit
425 mg open irritation test mild UCDS** 7/21/1965


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published lethal concentration: 4,000 ppm/4 hour N/R AMIHBC 4,119,1951
inhalation
rat
lethal concentration : 25,600 mg/m3/4 hour N/R VCVGK* -,379,1984
intraperitoneal
mouse
lethal dose (50 percent kill): 1,600 mg/kg Behavioral: Muscle weakness

Behavioral: Ataxia

Skin and Appendages: Other: Hair
NTIS** OTS0533623
intraperitoneal
rat
lethal dose (50 percent kill): 500 mg/kg N/R HYDRDA 3,201,1978
oral
mouse
lethal dose (50 percent kill): 3,550 mg/kg N/R 85GMAT -,103,1982
oral
rat
lethal dose (50 percent kill): 2,600 mg/kg N/R NTIS** OTS0534445
skin
guinea pig
lethal dose (50 percent kill): >16 gm/kg N/R FCTOD7 26,319,1988
skin
rat
lethal dose (50 percent kill): >20 mL/kg Skin: After systemic exposure: Dermatitis, other NTIS** OTS0533623
skin
rabbit
lethal dose (50 percent kill): 4,135 mg/kg N/R NTIS** OTS0534445


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 25,200 mg/kg/3 week- continuous Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) TOLED5 10,379,1982


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - RUSSIA short term exposure limit 3 mg/m3, JUN2003


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as a solvent extraction chemical
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
HYDRDA Hydrometallurgy. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1975-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.

Used as a solvent extraction chemical

RTECS Compound Description:
   Primary Irritant

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