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Registry of Toxic Effects of Chemical Substances (RTECS)

Glutaric acid

RTECS #

MA3740000

CAS #

110-94-1

Updated

January 2010

Molecular Weight

132.13

Molecular Formula

C5H8O4

Synonyms

1,3-Propanedicarboxylic acid
1,5-Pentanedioic acid
Pentanedioic acid

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mgHPV199 -,-,2001
skin /rabbit 0.5 gm mildHPV199 -,-,2001

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/rat 1000 mg/kg (6-15D pregnant)Reproductive: Other effects on femaleHPV199 -,-,2001

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/mouse lethal dose (50 percent kill): 6 gm/kgTumorigenic: Active as anti-cancer agentBIJOAK 34,1196,1940
oral/rat lethal dose (50 percent kill): 2750 mg/kgBehavioral: Tremor

Gastrointestinal: Gastritis

Gastrointestinal: Hypermotility, diarrhea
HPV199 -,-,2001
skin/rabbit lethal dose (50 percent kill): >10000 mg/kgHPV199 -,-,2001

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/Dog lowest published toxic dose: 67.5 gm/kg/90D- intermittentBehavioral: Food intake (animal)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
HPV199 -,-,2001
oral/rat lowest published toxic dose: 135 gm/kg/90D- intermittentNutritional and Gross Metabolic: Weight loss or decreased weight gainHPV199 -,-,2001

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X4684; Number of Industries 2; Total Number of Facilities 91; Number of Occupations 3; Total Number of Employees Exposed 1827; Total Number of Female Employees Exposed 432

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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