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Formic acid, methyl ester

RTECS #: LQ8925000

CAS #: 107-31-3


UPDATE: May 2009 MW: 60.06 MF: C2H4O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Formiate de methyle (French)
  2. Methyl formate
  3. Methyl formate (ACGIH:OSHA)
  4. Methyl methanoate
  5. Methyle (formiate de) (French)
  1. Methylester kyseliny mravenci (Czech)
  2. Methylformiaat (Dutch)
  3. Methylformiat (German)
  4. Metil (formiato di) (Italian)
  5. Mravencan methylnaty (Czech)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lethal concentration (50 percent kill): 5,200 mg/m3/4 hour N/R NTIS** OTS0556791
oral
mouse
lethal dose (50 percent kill): 675 mg/kg N/R NTIS** OTS0556689
oral
rat
lethal dose (50 percent kill): 475 mg/kg N/R NTIS** OTS0556689
oral
rabbit
lethal dose (50 percent kill): 1,622 mg/kg N/R IMSUAI 41,31,1972
skin
guinea pig
lethal dose (50 percent kill): >20 mL/kg N/R NTIS** OTS0556689
skin
rat
lethal dose (50 percent kill): >4 gm/kg N/R NTIS** OTS0556791
skin
rabbit
lethal dose (50 percent kill): >5 gm/kg N/R NTIS** OTS0556797


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 100 ppm;short term exposure limit 150 ppm DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
AMIHAB 20,517,1959


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 100 ppm (250 mg/m3) DTLVS* 3,165,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 100 ppm (250 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 100 ppm (250 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 100 ppm (250 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 100 ppm (250 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 100 ppm (246 mg/m3), short term exposure limit 150 ppm (368 mg/m3), , JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 100 ppm(250 mg/m3), short term exposure limit 150 ppm(373 mg/m3), MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 50 ppm (123 mg/m3), OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 100 ppm (250 mg/m3), short term exposure limit 150 ppm (375 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 100 ppm (250 mg/m3), FEB2006
Occupational Exposure Limit - GERMANY MAK 120 mg/m3 (50 mL/m3), 2005
Occupational Exposure Limit - KOREA time-weighted average 100 ppm (250 mg/m3), short term exposure limit 150 ppm (375 mg/m3), 2006
Occupational Exposure Limit - MEXICO time-weighted average 100 ppm (250 mg/m3);
short term exposure limit 150 ppm (375 mg/m3), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 250 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 100 ppm (246 mg/m3);
short term exposure limit 150 ppm (368 mg/m3), JAN2002
Occupational Exposure Limit - SWEDEN time-weighted average 100 ppm (250 mg/m3);
short term exposure limit 150 ppm (350 mg/m3), JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 50 ppm (125 mg/m3),KZG- week 200 ppm (500 mg/m3), Skin, DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 100 ppm (250 mg/m3), JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 100 ppm;
short term exposure limit 150 ppm
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 100 ppm;
short term exposure limit 150 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO METHYL FORMATE-air 10 hour time-weighted average 100 ppm;
short term exposure limit 150 ppm
NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 33850;
Number of Industries 6;
Total Number of Facilities 80;
Number of Occupations 22;
Total Number of Employees Exposed 7,738;
Total Number of Female Employees Exposed 1,402


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU.
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher information, see IOHSA5.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

RTECS Compound Description:
   Agricultural Chemical

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