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Registry of Toxic Effects of Chemical Substances (RTECS)

Formic acid, chloro-, isopropyl ester

RTECS #

LQ6475000

CAS #

108-23-6

Updated

July 2011

Molecular Weight

122.56

Molecular Formula

C4H7ClO2

Synonyms

Carbonochloride acid, 1-methylethyl ester
Chloroformic acid isopropyl ester
Isopropyl chlorocarbonate
Isopropyl chloromethanoate
Isopropylester kyseliny chlormravenci (Czech)

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 500 mg severeIHFCAY 6,1,1967
skin /rabbit 500 mgIHFCAY 6,1,1967

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat Lowest published lethal concentration: 200 ppm/5HLung, Thorax, or Respiration: DyspneaBJIMAG 27,1,1970
oral/mouse lethal dose (50 percent kill): 178 mg/kg37ASAA 4,758,1978
oral/rat lethal dose (50 percent kill): 1070 mg/kgIHFCAY 6,1,1967
skin/mouse lethal dose (50 percent kill): 12 mg/kg37ASAA 4,758,1978
skin/rabbit lethal dose (50 percent kill): 11300 mg/kgIHFCAY 6,1,1967

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 50 ppm/6H/2W- intermittentLung, Thorax, or Respiration: Other changes

Blood: Hemorrhage

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
BJIMAG 27,1,1970

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-AUSTRIAMAK-TMW 1 ppm (5 mg/m3);KZW 3 ppm (15 mg/m3), 2007
Occupational Exposure Limit-RUSSIAshort term exposure limit 0.1 mg/m3, JUN2003
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 5 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 1 ppm (5.1 mg/m3), OCT2007

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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