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Registry of Toxic Effects of Chemical Substances (RTECS)

Formic acid, chloro-, ethyl ester

RTECS #

LQ6125000

CAS #

541-41-3

Updated

July 2011

Molecular Weight

108.53

Molecular Formula

C3H5ClO2

Synonyms

Chlorocarbonate d'ethyle (French)
Chloroformic acid ethyl ester
Clhorameisensaeureaethylester (German)
ECF
Ethyl chlorocarbonate
Ethylchloorformiaat (Dutch)
Ethyle, chloroformiat d' (French)
Ethylester kyseliny chlormravenci (Czech)
Etil clorocarbonato (Italian)
Etil cloroformiato (Italian)
TL 423

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse Lowest published lethal concentration: 2260 mg/m3/10MNDRC** NDCrc-132,NOV1942
inhalation/rat lethal concentration (50 percent kill): 840 mg/m3/1HLung, Thorax, or Respiration: Changes in lung weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
NTIS** OTS0555045
intraperitoneal/mouse lowest published lethal dose: 15 mg/kgCBCCT* 6,220,1954
oral/rat lethal dose (50 percent kill): 270 mg/kgTXAPA9 42,417,1977
skin/rabbit lethal dose (50 percent kill): 7120 mg/kgTXAPA9 42,417,1977

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-AUSTRIAMAK-TMW 1 ppm (4.4 mg/m3);KZW 3 ppm (13.2 mg/m3), 2007
Occupational Exposure Limit-RUSSIAshort term exposure limit 0.2 mg/m3, Skin, JUN2003
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 4.4 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 1 ppm (4.5 mg/m3), OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X4668; Number of Industries 2; Total Number of Facilities 250; Number of Occupations 3; Total Number of Employees Exposed 2247; Total Number of Female Employees Exposed 187

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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