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Formic acid, chloro - , ethyl ester

RTECS #: LQ6125000

CAS #: 541-41-3


UPDATE: August 2006 MW: 108.53 MF: C3H5ClO2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. STANDARDS AND REGULATIONS:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Chlorocarbonate d'ethyle (French)
  2. Chloroformic acid ethyl ester
  3. Clhorameisensaeureaethylester (German)
  4. ECF
  5. Ethyl chlorocarbonate
  6. Ethylchloorformiaat (Dutch)
  1. Ethyle, chloroformiat d' (French)
  2. Ethylester kyseliny chlormravenci (Czech)
  3. Etil clorocarbonato (Italian)
  4. Etil cloroformiato (Italian)
  5. TL 423


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lowest published lethal concentration: 2,260 mg/m3/10 minute N/R NDRC** NDCrc-132,NOV1942
inhalation
rat
lethal concentration (50 percent kill): 840 mg/m3/1 hour Lung, Thorax, or Respiration: Changes in lung weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
NTIS** OTS0555045
intraperitoneal
mouse
lowest published lethal dose: 15 mg/kg N/R CBCCT* 6,220,1954
oral
rat
lethal dose (50 percent kill): 270 mg/kg N/R TXAPA9 42,417,1977
skin
rabbit
lethal dose (50 percent kill): 7,120 mg/kg N/R TXAPA9 42,417,1977


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 4.4 mg/m3, 2003
Occupational Exposure Limit - RUSSIA short term exposure limit 0.2 mg/m3, Skin, JUN2003
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 1 ppm (4.5 mg/m3), 2005


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4668;
Number of Industries 2;
Total Number of Facilities 250;
Number of Occupations 3;
Total Number of Employees Exposed 2,247;
Total Number of Female Employees Exposed 187


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in synthesis of pharmaceuticals, herbicides, plastics and other organic chemicals
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418)
NDRC** National Defense Research Committee, Office of Scientific Research and Development, Progress Report.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

Used in synthesis of pharmaceuticals, herbicides, plastics and other organic chemicals

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