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Registry of Toxic Effects of Chemical Substances (RTECS)

Ethylene

RTECS #

KU5340000

CAS #

74-85-1; 33060-30-9; 87701-64-2; 87701-65-3

Updated

September 201

Molecular Weight

28.06

Molecular Formula

C2H4

Synonyms

Acetene
Athylen (German)
Bicarburretted hydrogen
Elayl
Ethene
Ethylene (ACGIH:OSHA)
Liquid ethyene
Olefiant gas

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mammal (species unspecified) Lowest published lethal concentration: 950000 ppm/5MAEPPAE 138,65,1928
inhalation/mouse lethal concentration (50 percent kill): 95 ppm/2HVCVGH* -,46,1990
inhalation/mouse lowest published toxic concentration: 350000 mg/m3/2HBehavioral: General anestheticVCVGH* -,46,1990
inhalation/rat lowest published toxic concentration: 1000 ppm/2HLiver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases
NSAPCC 375(Suppl 1),74,2007

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 200 ppmDTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal No Adequate DataIMEMDT 19,157,1979
International Agency for Research on Cancer (IARC)Cancer Review:Human No Adequate DataIMEMDT 19,157,1979
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 60,45,1994
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 60,45,1994
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMEMDT 60,45,1994
TOXICOLOGY REVIEWCLPTAT 8,91,1967
TOXICOLOGY REVIEWTOLED5 138,1,2003
TOXICOLOGY REVIEWENTOX* -,271,2005
TOXICOLOGY REVIEWMUTAEX 19,169,2004
TOXICOLOGY REVIEWMUREAV 658,215,2008
TOXICOLOGY REVIEWMUREAV 544,313,2003
TOXICOLOGY REVIEWFCTOD7 47,1287,2009
TOXICOLOGY REVIEWMUREAV 678,76,2009

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESRED CompletedRBREV* -,254,1998
Mine Safety and Health Administration (MSHA) STANDARDASPHYXIANTS/GASESDTLWS* 3,19,1973
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-BELGIUMtime-weighted average 200 ppm (233 mg/m3), Asphyxiant, MAR2002
Occupational Exposure Limit-FINLANDtime-weighted average 200 ppm, NOV2011
Occupational Exposure Limit-MEXICOSimple asphyxiant, 2004
Occupational Exposure Limit-NEW ZEALANDSimple asphyxiant, JAN2002
Occupational Exposure Limit-RUSSIAshort term exposure limit 100 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 250 ppm (300 mg/m3);short term exposure limit 1000 ppm (1200 mg/m3), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 10000 ppm (11500 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 330 mg/m3, 2003
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)simple asphyxiant-inert gases and vaporsCFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)Simple asphyxiants - inert gas and vaporCFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 81826; Number of Industries 7; Total Number of Facilities 568; Number of Occupations 22; Total Number of Employees Exposed 12282; Total Number of Female Employees Exposed 2363
National Occupational Hazard Survey 1974Hazard Code 81826; Number of Industries 25; Total Number of Facilities 1071; Number of Occupations 43; Total Number of Employees Exposed 27450

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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