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Registry of Toxic Effects of Chemical Substances (RTECS)

Ethanol, 2-(2-(2-butoxyethoxy)ethoxy)-

RTECS #

KJ9450000

CAS #

143-22-6

Updated

October 1997

Molecular Weight

206.32

Molecular Formula

C10H22O4

Synonyms

2-(2-(2-Butoxyethoxy)ethoxy)ethanol
3,6,9-Trioxa-1-tridecanol
Butoxytriethylene glycol
Butoxytriglycol
Poly-Solv TB
Triethylene glycol monobutyl ether
Triethylene glycol n-butyl ether
Triglycol monobutyl ether

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 50 mg severeUCDS** 4/26/1965
eye /rabbit 20 mg/24H moderate85JCAE -,641,1986
skin /rabbit 10 mg/24H open irritation test mildAIHAAP 23,95,1962
skin /rabbit 500 mg/24H mild85JCAE -,641,1986

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/rat lethal dose (50 percent kill): 5300 mg/kgPeripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Altered sleep time (including change in righting reflex)
TSCAT* OTS 206801
skin/rabbit lethal dose (50 percent kill): 3540 µL/kgSkin: After topical application: Primary irritationAIHAAP 23,95,1962

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code M0984; Number of Industries 27; Total Number of Facilities 3319; Number of Occupations 20; Total Number of Employees Exposed 25310; Total Number of Female Employees Exposed 50
National Occupational Hazard Survey 1974Hazard Code M0984; Number of Industries 14; Total Number of Facilities 1954; Number of Occupations 28; Total Number of Employees Exposed 17644

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database
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