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Registry of Toxic Effects of Chemical Substances (RTECS)

Ethanol, 2-(2-butoxyethoxy)-, acetate

RTECS #

KJ9275000

CAS #

124-17-4

Updated

July 2013

Molecular Weight

204.30

Molecular Formula

C10H20O4

Synonyms

2-(2-Butoxyethoxy)ethanol acetate
2-(2-Butoxyethoxy)ethyl acetate
2-(2-Butoxyethoxy)ethylester kyseliny octove (Czech)
Acetic acid 2-(2-butoxyethoxy)ethyl ester
Butyl carbitol acetate
Butylkarbitolacetat (Czech)
Diethylene glycol butyl ether acetate
Diethylene glycol, monobutyl ether, acetate
Diglycol monobutyl ether acetate
Ektasolve DB acetate
Glycol ether DB aceatate

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 500 mg moderateAJOPAA 29,1363,1946
skin /rabbit 500 mg open irritation test mildUCDS** 12/29/1971

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): 72500 mg/m3/4HEye: Other eye effects

Lung, Thorax, or Respiration: Dyspnea

Lung, Thorax, or Respiration: Other changes
NTIS** OTS0571535
oral/chicken lethal dose (50 percent kill): 5 mL/kgJPETAB 93,26,1948
oral/guinea pig lethal dose (50 percent kill): 2340 mg/kgBehavioral: General anesthetic

Gastrointestinal: Other changes

Kidney, Ureter, and Bladder: Other changes
JIHTAB 23,259,1941
oral/mouse lethal dose (50 percent kill): 6600 µL/kgJPETAB 93,26,1948
oral/rabbit lethal dose (50 percent kill): 2260 mg/kgBehavioral: Sleep38MKAJ 2C,4028,1982
oral/rat lethal dose (50 percent kill): 6500 mg/kg28ZEAL 5,32,1976
skin/rabbit lethal dose (50 percent kill): 14500 mg/kgNPIRI* 1,27,1974

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
skin/rabbit lowest published toxic dose: 180 mL/kg/13W- intermittentBehavioral: Muscle weakness

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
JPETAB 93,26,1948

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-GERMANYMAK 10 ppm (85 mg/m3), 2011
Occupational Exposure Limit-SWEDENtime-weighted average 15 ppm (130 mg/m3);short term exposure limit 30 ppm (250 mg/m3), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 10 ppm (85 mg/m3), KZG-week 15 ppm (128 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 130 mg/m3, 2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 83639; Number of Industries 42; Total Number of Facilities 3243; Number of Occupations 46; Total Number of Employees Exposed 45220; Total Number of Female Employees Exposed 10562
National Occupational Hazard Survey 1974Hazard Code 83639; Number of Industries 35; Total Number of Facilities 1483; Number of Occupations 38; Total Number of Employees Exposed 21417

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database
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