Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Ethane, 1,1,1,2-tetrafluoro-

RTECS #

KI8842500

CAS #

811-97-2

Updated

July 2013

Molecular Weight

102.04

Molecular Formula

C2H2F4

Synonyms

1,1,1,2-Tetrafluoroethane
1,2,2,2-Tetrafluoroethane
Arcton 134a
F 134a
FC 134a
Fron 134a
HCFC 134a
HFA 134a
HFC 134a
Khladon 134a
Norflurane
R 134a
Refrigerant R134a
TG 134a

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
inhalation/rat 30 pph/6H (6-15D pregnant)Reproductive: Other effects on female

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)
NTIS** OTS0530569

Tumorigenic Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 50000 ppm/6H/2Y- intermittentTumorigenic: Neoplastic by RTECS criteria

Endocrine: Tumors
FAATDF 25,271,1995

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/Dog Lethal concentration: >32 pph/1HHETOEA 14,715,1995
inhalation/mouse lethal concentration (50 percent kill): 1700 gm/m3/2HTOVEFN (3),25,1996
inhalation/rat lethal concentration (50 percent kill): 1500 gm/m3/4HTOVEFN (3),25,1996

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWREPTED 29,125,2010
TOXICOLOGY REVIEWREPTED 29,1,2010
TOXICOLOGY REVIEWMUREAV 705,184,2010

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-AUSTRALIAtime-weighted average 1000 ppm (4240 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 1000 ppm (4200 mg/m3);KZW 4000 ppm (16800 mg/m3), 2007
Occupational Exposure Limit-GERMANYMAK 1000 ppm (4200 mg/m3), 2011
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 1000 ppm, JAN2002
Occupational Exposure Limit-RUSSIAshort term exposure limit 3000 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 500 ppm (2000 mg/m3);short term exposure limit 750 ppm (3000 mg/m3), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 1000 ppm (4200 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 4200 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 1000 ppm (4240 mg/m3), OCT2007

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
TOP