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Ethane, 1,1,1,2 - tetrafluoro -

RTECS #: KI8842500

CAS #: 811-97-2


UPDATE: May 2009 MW: 102.04 MF: C2H2F4


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. REPRODUCTIVE EFFECTS DATA:
  3. TUMORIGENIC DATA:
  4. ACUTE TOXICITY DATA:
  5. STANDARDS AND REGULATIONS:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 1,1,1,2 - Tetrafluoroethane
  2. 1,2,2,2 - Tetrafluoroethane
  3. Arcton 134a
  4. F 134a
  5. FC 134a
  6. Fron 134a
  7. HCFC 134a
  1. HFA 134a
  2. HFC 134a
  3. Khladon 134a
  4. Norflurane
  5. R 134a
  6. Refrigerant R134a
  7. TG 134a


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 30 pph/6 hour (6-15 day pregnant) Reproductive: Other effects on female

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)
NTIS** OTS0530569


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 50,000 ppm/6 hour/2 year- intermittent Tumorigenic: Neoplastic by RTECS criteria

Endocrine: Tumors
FAATDF 25,271,1995


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
dog
lethal concentration : >32 pph/1 hour N/R HETOEA 14,715,1995
inhalation
mouse
lethal concentration (50 percent kill): 1,700 gm/m3/2 hour N/R TOVEFN (3),25,1996
inhalation
rat
lethal concentration (50 percent kill): 1,500 gm/m3/4 hour N/R TOVEFN (3),25,1996


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - AUSTRALIA time-weighted average 1000 ppm (4240 mg/m3), JUL2008
Occupational Exposure Limit - GERMANY MAK 4200 mg/m3 (1000 mL/m3), 2005
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 4200 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 1000 ppm, JAN2002
Occupational Exposure Limit - RUSSIA short term exposure limit 3000 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 500 ppm (2000 mg/m3);
short term exposure limit 750 ppm (3000 mg/m3), JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 1000 ppm (4200 mg/m3), DEC2006
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 1000 ppm (4240 mg/m3), 2005


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
HETOEA Human & Experimental Toxicology. (Macmillan Press Ltd., Brunel Road, Houndmills, Basingstoke, Hampshire, RG21 2XS, UK) V.9- 1990-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown

RTECS Compound Description:
   Tumorigen
   Reproductive Effector

Click Here for Additional Information about RTECS

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