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Registry of Toxic Effects of Chemical Substances (RTECS)

Ethane, 1,2-dibutoxy-

RTECS #

KH9450000

CAS #

112-48-1

Updated

February 2003

Molecular Weight

174.32

Molecular Formula

C10H22O2

Synonyms

1,2-Dibutoxyethane
Butane, 1,1'-(1,2-ethanediylbis(oxy))bis- (9CI)
Dibutyl cellosolve
Dibutyl Oxitol
Dibutylether ethylenglykolu (Czech)
Ethylene glycol dibutyl ether
Glycol dibutyl ether

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /rabbit 500 mg open irritation test mildUCDS** 11/7/1957

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/rabbit lethal dose (16 percent kill): 1080 mg/kgVCVGK* -,319,1984
oral/rabbit lethal dose (50 percent kill): 1425 mg/kgVCVGK* -,319,1984
oral/rabbit lethal dose (84 percent kill): 1890 mg/kgVCVGK* -,319,1984
oral/rat lethal dose (16 percent kill): 870 mg/kgVCVGK* -,320,1984
oral/rat lethal dose (50 percent kill): 2650 mg/kgVCVGK* -,320,1984
oral/rat lethal dose (84 percent kill): 6100 mg/kgVCVGK* -,320,1984
skin/rabbit lethal dose (50 percent kill): 3560 µL/kgAMIHBC 10,61,1954
unreported route/rabbit lowest published toxic dose: 142.5 mg/kgEndocrine: Hyperglycemia

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Blood: Changes in erythrocyte (RBC) count
VCVGK* -,320,1984
unreported route/rat lowest published toxic dose: 265 mg/kgEndocrine: Hyperglycemia

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Blood: Changes in erythrocyte (RBC) count
VCVGK* -,320,1984
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