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Registry of Toxic Effects of Chemical Substances (RTECS)

Diethylene glycol, dinitrate

RTECS #

ID6825000

CAS #

693-21-0

Updated

June 2000

Molecular Weight

196.14

Molecular Formula

C4H8N2O7

Synonyms

Bis(hydroxyaethyl)-aether-dinitrat (German)
Di(hydroxyethyl) ether dinitrate
Diethylenglykoldinitrate (Czech)
Diglycol (dinitrate de) (French)
Diglycoldinitraat (Dutch)
Diglykoldinitrat (German)
Dinitrate de diethylene-glycol (French)
Dinitrodiglicol (Italian)
Dinitrodiglykol (Czech)
Ethanol, 2,2'-oxybisdinitrate

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 1250 mg/kgSTGNBT -,91,1999
oral/guinea pig lethal dose (50 percent kill): 650 mg/kgBrain and Coverings: Recordings from specific areas of CNS

Cardiac: EKG changes not diagnostic of above

Behavioral: Convulsions or effect on seizure threshold
STGNBT -,91,1999
oral/mouse lethal dose (50 percent kill): 1250 mg/kgBehavioral: Change in motor activity (specific assay)

Lung, Thorax, or Respiration: Cyanosis
JHEMA2 17,114,1973
oral/rabbit lethal dose (50 percent kill): 1060 mg/kgBrain and Coverings: Recordings from specific areas of CNS

Cardiac: Other changes

Behavioral: Convulsions or effect on seizure threshold
STGNBT -,91,1999
oral/rat lethal dose (50 percent kill): 753 mg/kgBehavioral: Tremor

Behavioral: Muscle contraction or spasticity

Behavioral: Irritability
ATDAEI 12,602,1993
skin/rabbit Lethal dose: >2 gm/kgBehavioral: Tremor

Behavioral: Muscle contraction or spasticity

Behavioral: Irritability
ATDAEI 12,600,1993
unreported route/mammal (species unspecified) lethal dose (50 percent kill): 1250 mg/kgGISAAA 39(11),13,1974

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 860 µg/m3/17W- intermittentCardiac: EKG changes not diagnostic of above

Blood: Normocytic anemia

Blood: Luekopenia
STGNBT -,91,1999

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database
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