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Registry of Toxic Effects of Chemical Substances (RTECS)

Decane

RTECS #

HD6550000

CAS #

124-18-5

Updated

April 2012

Molecular Weight

142.32

Molecular Formula

C10H22

Synonyms

n-Decane
UN 2247

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /pig 1200 µL/4D- intermittent mildTOPADD 33,258,2005

Tumorigenic Data and References

Route/OrganismDoseEffectReference
skin/mouse lowest published toxic dose: 25 gm/kg/52W- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Skin and Appendages: Tumors

Tumorigenic: Tumors at site of application
TXAPA9 9,70,1966

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lethal concentration (16 percent kill): 42000 mg/m3/2HVCVGH* -,40,1990
inhalation/mouse lethal concentration (50 percent kill): 72300 mg/m3/2HVCVGH* -,40,1990
inhalation/mouse lethal concentration (84 percent kill): 90000 mg/m3/2HVCVGH* -,40,1990
inhalation/mouse lethal concentration (50 percent kill): 72300 mg/m3/2HBehavioral: AntipsychoticGTPZAB 26(8),53,1982
inhalation/rat lethal concentration (50 percent kill): >1369 ppm/8HPHTOEH 62,259,1988
inhalation/rat lethal concentration (50 percent kill): 72300 mg/m3/2HENTOX* -,727,2005
intravenous/mouse lowest published lethal dose: 912 mg/kgBehavioral: Altered sleep time (including change in righting reflex)APTOA6 37,56,1975

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 500 mg/m3/30D- continuousBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Catalases
VCVGH* -,40,1990
inhalation/rat lowest published toxic concentration: 800 ppm/4W- intermittentReproductive: Paternal effects: Testes, epididymis, sperm ductTOXID9 60,325,2001

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWTOLED5 127,111,2002
TOXICOLOGY REVIEWENTOX* -,727,2005

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-DENMARKtime-weighted average 45 ppm (250 mg/m3), MAY2011
Occupational Exposure Limit-ICELANDtime-weighted average 45 ppm (250 mg/m3), NOV2011
Occupational Exposure Limit-SWEDENtime-weighted average 350 mg/m3;short term exposure limit 500 mg/m3, JUN2005

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code A1315; Number of Industries 3; Total Number of Facilities 80; Number of Occupations 4; Total Number of Employees Exposed 1667; Total Number of Female Employees Exposed 43
National Occupational Hazard Survey 1974Hazard Code A1315; Number of Industries 3; Total Number of Facilities 666; Number of Occupations 3; Total Number of Employees Exposed 716

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1996: Volatile organic compound, 2549
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