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Registry of Toxic Effects of Chemical Substances (RTECS)

Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)methyl ester

RTECS #

GZ1730000

CAS #

7696-12-0; 28643-67-6

Updated

August 2008

Molecular Weight

331.45

Molecular Formula

C19H25NO4

Synonyms

(+-)-cis/trans-Phthalthrin
(1-Cyclohexane-1,2-dicarboximido)methyl chrysanthemumate
2,3,4,5-Tetrahydrophthalimidomethylchrysanthemate
3,4,5,6-Tetrahydrophthalimidomethyl cis and trans dl chrysanthemummonocarboxylic acid
3,4,5,6-Tetrahydro-phthalimidomethylester der dl-cis-trans-chrysanthemumsaeure (German)
Bioneopynamin
d-Phthalthrin
d-Tetramethrin
ENT 27339
FMC-9260
Insectol
Multicide
N-(3,4,5,6-Tetrahydrophthalimido)-methyl dl-cis-trans-chrysanthemate
Neopinamin
Neo-pynamin
Neopynamin forte
NIA-9260
Niagara nia-9260
NSC 190939
Phthalthrin
SP 1103 forte
SP-1103
Sumitomo SP-1103
Tetralate
Tetramethrin
Tetramethrine (French)

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg/1H mildOYYAA2 24,179,1982

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium50 mg/L (+enzymatic activation step)ZYDXDM 14,1,1985
Unscheduled DNA Synthesisother cell types/human50 mg/LZYDXDM 14,1,1985

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lethal concentration (50 percent kill): >2 gm/m3YKYUA6 36,533,1985
inhalation/rat lethal concentration (50 percent kill): >2500 mg/m3/3H85JFAN A388,1983
intraperitoneal/mouse lethal dose (50 percent kill): 527 mg/kgBehavioral: Tremor

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea
OYYAA2 24,179,1982
intraperitoneal/rat lethal dose (50 percent kill): 548 mg/kgBehavioral: Tremor

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea
OYYAA2 24,179,1982
intravenous/rat lethal dose (50 percent kill): 3500 µg/kgABCHA6 32,628,1968
oral/chicken lethal dose (50 percent kill): 5 gm/kg28ZEAL 5,220,1976
oral/duck lethal dose (50 percent kill): >1 gm/kgPEMNDP 9,807,1991
oral/mouse lethal dose (50 percent kill): 1 gm/kgABCHA6 28,914,1965
oral/quail lethal dose (50 percent kill): >1 gm/kgPEMNDP 9,807,1991
oral/rat lethal dose (50 percent kill): 4640 mg/kgYKYUA6 35,1315,1984
skin/guinea pig lethal dose (50 percent kill): >20 gm/kgBehavioral: Somnolence (general depressed activity)

Skin and Appendages: Other: Hair
OSDIAF 16,509,1967
skin/mouse lethal dose (50 percent kill): >15 gm/kgSPEADM 78-1,6,1978
skin/rat lethal dose (50 percent kill): >2500 mg/kgBehavioral: Tremor

Behavioral: Excitement

Kidney, Ureter, and Bladder: Urine volume increased
GISAAA 49(4),90,1984
subcutaneous/mouse lethal dose (50 percent kill): 1950 mg/kgBehavioral: Tremor

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea
OYYAA2 24,179,1982
subcutaneous/rat lethal dose (50 percent kill): 5700 mg/kgBehavioral: Somnolence (general depressed activity)

Gastrointestinal: Hypermotility, diarrhea

Kidney, Ureter, and Bladder: Urine volume increased
OSDIAF 16,509,1967

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
subcutaneous/rat lowest published toxic dose: 15 mg/kg/3D- intermittentRelated to Chronic Data: Changes in uterine weightJTEHF8 68,2277,2005

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESSupportedRBREV* -,212,1998
Occupational Exposure Limit-RUSSIAshort term exposure limit 5 mg/m3, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X2712; Number of Industries 10; Total Number of Facilities 633; Number of Occupations 13; Total Number of Employees Exposed 9244; Total Number of Female Employees Exposed 1759
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