Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-, (5-benzyl-3-furyl)methylester

RTECS #

GZ1310000

CAS #

10453-86-8

Updated

November 2006

Molecular Weight

338.48

Molecular Formula

C22H26O3

Synonyms

(5-Benzyl-3-furyl) methyl-2,2-dimethyl-3-(2-methylpropenyl)-cyclopropanecarboxylate
5-Benzyl-3-furylmethyl(+-)-cis,trans-chrysanthemate
ARI-B
Benzofuroline
Benzyfuroline
Chrysron
Crossfire
Dimethyl 3-(2-methyl-1-propenyl)cyclopropanecarboxylate
Enforcer
ENT 27474
FMC 17370
For-syn
NIA 17370
NRDC 104
NSC 195022
OMS-1206
Penick 1382
Penncapthrin
Premgard
Pyresthrin
Resmethrin
Resmetrina (Portuguese)
S.B. penick 1382
SBP-1382
Synthrin

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/Dog Lethal concentration: >420 mg/m3/4HNTIS** AD747-345
inhalation/rat Lethal concentration: >420 mg/m3/4HNTIS** AD747-345
intraperitoneal/mammal (species unspecified) lethal dose (50 percent kill): >1 gm/kgOYYAA2 3,325,1969
intraperitoneal/mouse lethal dose (50 percent kill): >1 gm/kgPeripheral Nerve and Sensation: Sensory change involving peripheral nerve

Behavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold
OYYAA2 3,325,1969
intraperitoneal/rat lowest published lethal dose: 19200 mg/kgNTIS** AD747-345
intravenous/Dog lowest published lethal dose: 250 mg/kgBehavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Gastrointestinal: Changes in structure or function of salivary glands
NTIS** AD747-345
intravenous/rabbit lowest published lethal dose: 250 mg/kgBehavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold

Behavioral: Irritability
NTIS** AD747-345
intravenous/rat lowest published lethal dose: 160 mg/kgBehavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Lung, Thorax, or Respiration: Acute pulmonary edema
BIOGAL 41,283,1975
oral/mammal (species unspecified) lethal dose (50 percent kill): >3375 mg/kgOYYAA2 3,325,1969
oral/mouse lethal dose (50 percent kill): 300 mg/kgABCHA6 37,2681,1973
oral/rat lethal dose (50 percent kill): 1244 mg/kgFAATDF 7,299,1986
oral/rat lowest published toxic dose: 116.6 mg/kgLiver: Other changes

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases
TOXID9 90,245,2006
oral/wild bird lethal dose (50 percent kill): 75 mg/kgAECTCV 12,355,1983
skin/mouse lethal dose (50 percent kill): >5 gm/kgBOCKAF 34,157,1969
skin/rabbit lethal dose (50 percent kill): 2500 mg/kgSPEADM 78-1,9,1978
skin/rat lethal dose (50 percent kill): 3 gm/kgYKYUA6 38,1331,1987
subcutaneous/mouse lethal dose (50 percent kill): >2 gm/kgBOCKAF 34,157,1969
subcutaneous/rat lethal dose (50 percent kill): >5 gm/kgBOCKAF 34,157,1969

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 6500 mg/kg/10D- intermittentBehavioral: Muscle weaknessARTODN 53,297,1983

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESSupportedRBREV* -,147,1998

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X3120; Number of Industries 13; Total Number of Facilities 1693; Number of Occupations 11; Total Number of Employees Exposed 27595; Total Number of Female Employees Exposed 3999

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Negative: In vitro UDS-human fibroblast; S cerevisiae-homozygosis
On EPA IRIS database
TOP