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Cyclopropanecarboxylic acid, 2,2 - dimethyl - 3 - (2 - methylpropenyl) - , (5 - benzyl - 3 - furyl) methyl ester

RTECS #: GZ1310000

CAS #: 10453-86-8


UPDATE: November 2006 MW: 338.48 MF: C22H26O3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. (5 - Benzyl - 3 - furyl) methyl - 2,2 - dimethyl - 3 - (2 - methylpropenyl) - cyclopropanecarboxylate
  2. 5 - Benzyl - 3 - furylmethyl (+ - ) - cis,trans - chrysanthemate
  3. ARI - B
  4. Benzofuroline
  5. Benzyfuroline
  6. Chrysron
  7. Crossfire
  8. Dimethyl 3 - (2 - methyl - 1 - propenyl) cyclopropanecarboxylate
  9. ENT 27474
  10. Enforcer
  11. FMC 17370
  12. For - syn
  13. NIA 17370
  1. NRDC 104
  2. NSC 195022
  3. OMS - 1206
  4. Penick 1382
  5. Penncapthrin
  6. Premgard
  7. Pyresthrin
  8. Resmethrin
  9. Resmetrina (Portuguese)
  10. S.B. penick 1382
  11. SBP - 1382
  12. Synthrin


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
dog
lethal concentration : >420 mg/m3/4 hour N/R NTIS** AD747-345
inhalation
rat
lethal concentration : >420 mg/m3/4 hour N/R NTIS** AD747-345
intraperitoneal
mammal (species unspecified)
lethal dose (50 percent kill): >1 gm/kg N/R OYYAA2 3,325,1969
intraperitoneal
mouse
lethal dose (50 percent kill): >1 gm/kg Peripheral Nerve and Sensation: Sensory change involving peripheral nerve

Behavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold
OYYAA2 3,325,1969
intraperitoneal
rat
lowest published lethal dose: 19,200 mg/kg N/R NTIS** AD747-345
intravenous
dog
lowest published lethal dose: 250 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Gastrointestinal: Changes in structure or function of salivary glands
NTIS** AD747-345
intravenous
rat
lowest published lethal dose: 160 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Lung, Thorax, or Respiration: Acute pulmonary edema
BIOGAL 41,283,1975
intravenous
rabbit
lowest published lethal dose: 250 mg/kg Behavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold

Behavioral: Irritability
NTIS** AD747-345
oral
wild bird
lethal dose (50 percent kill): 75 mg/kg N/R AECTCV 12,355,1983
oral
mammal (species unspecified)
lethal dose (50 percent kill): >3,375 mg/kg N/R OYYAA2 3,325,1969
oral
mouse
lethal dose (50 percent kill): 300 mg/kg N/R ABCHA6 37,2681,1973
oral
rat
lethal dose (50 percent kill): 1,244 mg/kg N/R FAATDF 7,299,1986
oral
rat
lowest published toxic dose: 116.6 mg/kg Liver: Other changes

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases
TOXID9 90,245,2006
subcutaneous
mouse
lethal dose (50 percent kill): >2 gm/kg N/R BOCKAF 34,157,1969
subcutaneous
rat
lethal dose (50 percent kill): >5 gm/kg N/R BOCKAF 34,157,1969
skin
mouse
lethal dose (50 percent kill): >5 gm/kg N/R BOCKAF 34,157,1969
skin
rat
lethal dose (50 percent kill): 3 gm/kg N/R YKYUA6 38,1331,1987
skin
rabbit
lethal dose (50 percent kill): 2,500 mg/kg N/R SPEADM 78-1,9,1978


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 6,500 mg/kg/10 day- intermittent Behavioral: Muscle weakness ARTODN 53,297,1983


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Supported RBREV* -,147,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X3120;
Number of Industries 13;
Total Number of Facilities 1,693;
Number of Occupations 11;
Total Number of Employees Exposed 27,595;
Total Number of Female Employees Exposed 3,999


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA GENETOX PROGRAM 1988, Negative: In vitro UDS-human fibroblast; S cerevisiae-homozygosis
Used as an insecticide
On EPA IRIS database


REFERENCES:

CODEN
REFERENCE

ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961-
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973-
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974-
BIOGAL Biologico. (Instituto Biologica, Av. Cons. Rodriques Alves, 1252, CEP 04014, Sao Paulo, Brazil) V.1- 1935-
BOCKAF Bochu Kagaku. Scientific Pest Control. (Kyoto, Japan) V.1-42, 1937-77. Discontinued.
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740)
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-

Used as an insecticide

RTECS Compound Description:
   Agricultural Chemical
   Mutagen

Click Here for Additional Information about RTECS

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