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Registry of Toxic Effects of Chemical Substances (RTECS)

Cyclohexanecarboxylic acid, 4-(cyclopropylhydroxymethylene)-3,5-dioxo-, ethyl ester

RTECS #

GU8473500

CAS #

95266-40-3

Updated

August 2003

Molecular Weight

252.29

Molecular Formula

C13H16O5

Synonyms

4-(Cyclopropyl-alpha-hydroxymethylene)-3,5-dioxocyclohexanecarboxylic acid ethyl ester
Cimectacarb
Ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate
Moddus
Primo
Trinexapac-Ethyl
Trinexapac-ethyl

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): >5300 mg/kgNNGADV 22,351,1997
oral/mouse lethal dose (50 percent kill): 5409 mg/kgNNGADV 22,351,1997
oral/rat lethal dose (50 percent kill): 4460 mg/kgPEMNDP 9,351,1991
skin/rat lethal dose (50 percent kill): >4 gm/kgPEMNDP 9,351,1991

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/Dog lowest published toxic dose: 46125 mg/kg/7W- intermittentBrain and Coverings: Changes in brain weight

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Endocrine: Other changes
NTIS** OTS0543163
oral/Dog lowest published toxic dose: 34125 mg/kg/13W- intermittentEndocrine: Other changesNTIS** OTS0543199
oral/rat lowest published toxic dose: 47 gm/kg/28D- intermittentCardiac: Changes in heart weight

Kidney, Ureter, and Bladder: Changes in bladder weight

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)
NTIS** OTS0543162
oral/rat lowest published toxic dose: 27300 mg/kg/13W- intermittentKidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Kidney, Ureter, and Bladder: Other changes
NTIS** OTS0543198

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESActive registrationRBREV* -,399,1998

Status in Federal Agencies

OrganizationReference
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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