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Registry of Toxic Effects of Chemical Substances (RTECS)

Cobalt(2+) sulfide

RTECS #

GG3325000

CAS #

1317-42-6

Updated

September 201

Molecular Weight

90.99

Molecular Formula

CoS

Synonyms

Cobalt monosulfide
Cobalt sulfide (amorphous)
Cobalt(II) sulfide
Cobaltous sulfide

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
DNA Damageovary/hamster10 mg/LCRNGDP 3,657,1982
morphological transformembryo/hamster1 mg/LCNREA8 42,2757,1982
mutation in mammalian somatic cellslung/hamster25 mg/m3MUREAV 370,133,1996

Tumorigenic Data and References

Route/OrganismDoseEffectReference
intramuscular/rat lowest published toxic dose: 180 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Musculoskeletal: Tumors

Tumorigenic: Tumors at site of application
CNREA8 22,158,1962

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/rat lethal dose (50 percent kill): >5 gm/kgNutritional and Gross Metabolic: Weight loss or decreased weight gainATDAEI 1,693,1992

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.02 mg(Co)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Confirmed animal carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal Limited EvidenceIMEMDT 52,363,1991
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 52,363,1991
International Agency for Research on Cancer (IARC)Cancer Review:Group 2BIMEMDT 52,363,1991
TOXICOLOGY REVIEWFCTXAV 9,105,1971
TOXICOLOGY REVIEWHBTME* ,511,2007

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-FINLANDtime-weighted average 0.02 mg(Co)/m3, NOV2011
Occupational Exposure Limit-HUNGARYtime-weighted average 0.1 mg(Co)/m3, short term exposure limit 0.4 mg(Co)/m3, SEP2000
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.05 mg(Co)/m3, 2B carc, a1 sen, s2 sen, MAY2012
Occupational Exposure Limit-SWEDENtime-weighted average 0.05 mg(Co)/m3, Sen, JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.05 mg(Co)/m3, carc 2, inhal, skin, sen, JAN2011
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.1 mg(Co)/m3, sen, OCT2007

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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