Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Chromic acid, zinc salt

RTECS #

GB3290000

CAS #

13530-65-9; 1308-13-0; 1328-67-2; 14675-41-3

Updated

September 201

Molecular Weight

181.37

Molecular Formula

CrO4·Zn

Synonyms

Buttercup Yellow
C.I. 77955
Chromium zinc oxide (ZrCrO4)
Zinc chromate (ACGIH:OSHA)
Zinc chromate AM
Zinc chromate C
Zinc chromate O
Zinc chromate T
Zinc chromate Z
Zinc chromate(VI) hydroxide
Zinc chromates
Zinc chromates (ACGIH)
Zinc chrome
Zinc chrome (anti-corrosion)
Zinc Chrome Yellow
Zinc chromium oxide (ZrCrO4)
Zinc hydroxychromate
Zinc tetraoxychromate
Zinc tetraoxychromate 76A
Zinc tetraoxychromate 780B
Zincro ZTO
ZTO

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysisother cell types/human500 mg/LBJCAAI 44,219,1981
Cytogenetic Analysisovary/hamster5 mg/LBJCAAI 44,219,1981
DNA inhibitionkidney/hamster50 mg/LBJCAAI 44,219,1981
morphological transformkidney/hamster14 mg/LTECSDY 12,185,1986
morphological transformembryo/hamster10 µmol/LCNREA8 39,193,1979
mutation in mammalian somatic cellslung/hamster4 mg/LMUREAV 67,55,1979
mutation in microorganisms/Salmonella typhimurium800 ng/plate (+enzymatic activation step)MUREAV 156,219,1985
other mutation test systemsother cell types/human500 mg/LBJCAAI 44,219,1981
other mutation test systemskidney/hamster50 mg/LBJCAAI 44,219,1981
sister chromatid exchangeovary/hamster100 µg/LMUREAV 156,219,1985

Tumorigenic Data and References

Route/OrganismDoseEffectReference
implant/rat lowest published toxic dose: 12928 µg/kgTumorigenic: Carcinogenic by RTECS criteria

Lung, Thorax, or Respiration: Bronchogenic carcinoma
BJIMAG 43,243,1986
inhalation/man lowest published toxic concentration: 5 mg/m3/8H/7Y- intermittentTumorigenic: Carcinogenic by RTECS criteria

Lung, Thorax, or Respiration: Bronchogenic carcinoma
BJIMAG 32,62,1975
subcutaneous/rat lowest published toxic dose: 135 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application
PBPHAW 14,47,1978

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intravenous/mouse lowest published lethal dose: 30 mg/kgAQMOAC #70-15,1970

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.01 mg(Cr)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Confirmed human carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 23,205,1980
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 49,49,1990
International Agency for Research on Cancer (IARC)Cancer Review:Human Sufficient EvidenceIMEMDT 23,205,1980
International Agency for Research on Cancer (IARC)Cancer Review:Human Sufficient EvidenceIMEMDT 49,49,1990
International Agency for Research on Cancer (IARC)Cancer Review:Group 1IMEMDT 49,49,1990
TOXICOLOGY REVIEW85DHAX Cr,22,1974
TOXICOLOGY REVIEWENTOX* -,602,2005
TOXICOLOGY REVIEWMUREAV 533,36,2003
TOXICOLOGY REVIEWHBTME* ,487,2007

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.01 mg(Cr)/m3, Carcinogen, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.01 mg(Cr)/m3, Carcinogen, MAR2002
Occupational Exposure Limit-BELGIUMtime-weighted average 0.01 mg(Cr)/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.005 mg(Cr)/m3, MAY2011
Occupational Exposure Limit-FRANCEVME 0.05 mg(Cr)/m3, FEB2006
Occupational Exposure Limit-GERMANYMAK 0.1 mg(Zn)/m3, resp, 2011
Occupational Exposure Limit-GERMANYMAK 2 mg(Zn)/m3, inhal, 2011
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.05 mg(Cr)/m3, a2 sen, s1 sen, MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 0.01 mg/m3, carcinogen, 2006
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.01 mg(Cr)/m3, carcinogen, JAN2002
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.05 mg(Cr)/m3, sen, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.02 mg(CrO3)/m3, JAN1999
Occupational Exposure Limit-POLANDtime-weighted average 0.1 mg/m3, short term exposure limit 0.3 mg/m3, JAN1999
Occupational Exposure Limit-SWEDENtime-weighted average 0.005 mg(Cr)/m3;short term exposure limit 0.015 mg(Cr)/m3, Carcinogen, Sen, JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.01 mg(Cr)/m3, carc 1, inhal, sen, JAN2011
Occupational Exposure Limit-SWITZERLANDMAK-week 0.05 mg(Cr)/m3, carc 1, inhal, skin, sen, JAN2011
Occupational Exposure Limit-SWITZERLANDMAK-week 0.1 mg(Zn)/m3, KZG-week 0.4 mg(Zn)/m3, resp, JAN2011
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.05 mg(Cr)/m3, carc, sen, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.1 mg(CrO3)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)ceiling concentration 0.1 mg(CrO3)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)ceiling concentration 0.1 mg(CrO3)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)ceiling concentration 0.1 mg(CrO3)/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ZINC CHROMATE-air10H Carcinogen time-weighted average 0.001 mg/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code M0900; Number of Industries 71; Total Number of Facilities 5081; Number of Occupations 57; Total Number of Employees Exposed 58924; Total Number of Female Employees Exposed 4190
National Occupational Hazard Survey 1974Hazard Code M0900; Number of Industries 108; Total Number of Facilities 9236; Number of Occupations 57; Total Number of Employees Exposed 79219

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat; Cell transform.-SA7/SHE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH CURRENT INTELLIGENCE BULLETIN 4, 1975/1976
NTP 10th Report on Carcinogens,2002:Known to be a human carcinogen
TOP