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Registry of Toxic Effects of Chemical Substances (RTECS)

Chromic acid, strontium salt (1:1)

RTECS #

GB3240000

CAS #

7789-06-2; 54322-60-0

Updated

September 201

Molecular Weight

203.62

Molecular Formula

CrO4·Sr

Synonyms

C.I. 77839
C.I. Pigment Yellow 32
Deep Lemon Yellow
Pigment Yellow 32
Strontium chromate
Strontium chromate (1:1)
Strontium chromate (ACGIH)
Strontium chromate (VI)
Strontium chromate 12170
Strontium chromate A
Strontium chromate X-2396
Strontium Yellow
Sutokuro T
X 2396

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
morphological transformembryo/hamster100 µg/LCRNGDP 12,1811,1991
mutation in microorganisms/Salmonella typhimurium800 ng/plate (+enzymatic activation step)MUREAV 156,219,1985
sister chromatid exchangeovary/hamster100 µg/LMUREAV 156,219,1985

Tumorigenic Data and References

Route/OrganismDoseEffectReference
implant/rat lowest published toxic dose: 125 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application
AIHAAP 20,274,1959
intratracheal/rat lowest published toxic dose: 40 mg/kg/34W- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors

Tumorigenic: Tumors at site of application
AEHLAU 5,445,1962

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 40 mg/m3Behavioral: Alteration of classical conditioningVCVN1* -,128,1988
inhalation/rat lowest published toxic concentration: 20 mg/m3Nutritional and Gross Metabolic: Other changesVCVN1* -,128,1988
intratracheal/rat lethal dose (50 percent kill): 16.6 mg/kgVCVN1* -,128,1988
oral/mammal (species unspecified) lethal dose (50 percent kill): >1500 mg/kgGTPZAB 19(8),43,1975
oral/rat lethal dose (50 percent kill): 3118 mg/kgVCVN1* -,128,1988

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.0005 mg(Cr)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Suspected human carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 23,205,1980
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 49,49,1990
International Agency for Research on Cancer (IARC)Cancer Review:Human Sufficient EvidenceIMEMDT 23,205,1980
International Agency for Research on Cancer (IARC)Cancer Review:Human Sufficient EvidenceIMEMDT 49,49,1990
International Agency for Research on Cancer (IARC)Cancer Review:Group 1IMEMDT 49,49,1990
TOXICOLOGY REVIEWENTOX* -,602,2005
TOXICOLOGY REVIEWHBTME* ,487,2007

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.5 mg(Cr)/m3DTLVS* 3,35,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-ARAB Republic of Egypttime-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.05 mg(Cr)/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.0005 mg/m3, Carcinogen, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.0005 mg(Cr)/m3, carc, MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 0.05 mg(CrO4)/m3, NOV2011
Occupational Exposure Limit-FRANCEVME 0.05 mg(Cr)/m3, FEB2006
Occupational Exposure Limit-HUNGARYceiling concentration 0.05 mg/m3, Carcinogen, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 0.0005 mg(Cr)/m3, carc, NOV2011
Occupational Exposure Limit-INDIAtime-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.05 mg(Cr)/m3, a2 sen, s1 sen, MAY2012
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.001 mg(Cr)/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.02 mg(CrO3)/m3, JAN1999
Occupational Exposure Limit-PERUtime-weighted average 0.0005 mg/m3, JUL2005
Occupational Exposure Limit-POLANDtime-weighted average 0.5 mg/m3, JAN1999
Occupational Exposure Limit-SWEDENtime-weighted average 0.005 mg(Cr)/m3;short term exposure limit 0.015 mg(Cr)/m3, Carcinogen, Sen, JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.05 mg(Cr)/m3, carc 1, inhal, skin, sen, JAN2011
Occupational Exposure Limit-THAILANDtime-weighted average 1 mg/m3, JAN1993
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.05 mg(Cr)/m3, carc, sen, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)ceiling concentration 0.1 mg(CrO3)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)ceiling concentration 0.1 mg(CrO3)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)ceiling concentration 0.1 mg(CrO3)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)ceiling concentration 0.1 mg(CrO3)/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CHROMIUM(VI)-air10H Carcinogen time-weighted average 0.001 mg(Cr)/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code M2287; Number of Industries 28; Total Number of Facilities 1164; Number of Occupations 36; Total Number of Employees Exposed 38744; Total Number of Female Employees Exposed 2855
National Occupational Hazard Survey 1974Hazard Code M2287; Number of Industries 19; Total Number of Facilities 627; Number of Occupations 28; Total Number of Employees Exposed 10145

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH CURRENT INTELLIGENCE BULLETIN 4, 1975/1976
NTP 11th Report on Carcinogens,2004:Known to be human carcinogen
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