Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Carbonochloridic acid, methyl ester

RTECS #

FG3675000

CAS #

79-22-1

Updated

July 2013

Molecular Weight

94.50

Molecular Formula

C2H3ClO2

Synonyms

Chlorameisensaeure methylester (German)
Chlorocarbonate de methyle (French)
Chlorocarbonic acid methyl ester
Chloroformiate de methyle (French)
Chloroformic acid methyl ester
Formic acid, chloro-, methyl ester
MCF
Methoxycarbonyl chloride
Methyl chlorocarbonate
Methylchloorformiaat (Dutch)
Methylester kyseliny chlormravenci (Czech)
Methylester kyseliny chloruhlicite (Czech)
Metilcloroformiato (Italian)
RCRA waste number U156
TL 438

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/cat Lowest published lethal concentration: 1500 mg/m3/30MGISAAA 42(5),97,1977
inhalation/man lowest published toxic concentration: 5 mg/m3Eye: Conjunctiva irritation

Lung, Thorax, or Respiration: Other changes
GISAAA 42(5),97,1977
inhalation/mouse lethal concentration (50 percent kill): 185 mg/m3/2HBehavioral: Convulsions or effect on seizure threshold

Behavioral: Excitement

Behavioral: Muscle weakness
GISAAA 42(5),97,1977
inhalation/rat lethal concentration (50 percent kill): 88 ppm/1HTXAPA9 42,417,1977
intraperitoneal/mouse lethal dose (50 percent kill): 40 mg/kgNTIS** AD691-490
oral/guinea pig lethal dose (50 percent kill): 140 mg/kgGISAAA 42(5),97,1977
oral/mouse lethal dose (50 percent kill): 67 mg/kgGISAAA 42(5),97,1977
oral/rat lethal dose (50 percent kill): 60 mg/kgGISAAA 42(5),97,1977
skin/mouse lethal dose (50 percent kill): 1750 mg/kgGISAAA 42(5),97,1977
skin/rabbit lethal dose (50 percent kill): 7120 mg/kgTXAPA9 42,417,1977

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lowest published toxic concentration: 640 µg/m3/17W- intermittentBlood: Other changes

Nutritional and Gross Metabolic: Body temperature decrease
GISAAA 42(5),97,1977
inhalation/rat lowest published toxic concentration: 34360 µg/m3/6H/4W- intermittentLung, Thorax, or Respiration: Respiratory stimulation

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
NTIS** OTS0570775
inhalation/rat lowest published toxic concentration: 720 µg/m3/17W- intermittentCardiac: Changes in heart weight

Blood: Changes in erythrocyte (RBC) count

Nutritional and Gross Metabolic: Body temperature decrease
GISAAA 42(5),97,1977

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-GERMANYMAK 0.2 ppm (0.78 mg/m3 ), 2011
Occupational Exposure Limit-RUSSIAshort term exposure limit 0.05 mg/m3, Skin, JUN2003
Occupational Exposure Limit-SWITZERLANDMAK-week 0.2 ppm (0.78 mg/m3), KZG-week 0.4 ppm (1.56 mg/m3), JAN2011

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X4785; Number of Industries 2; Total Number of Facilities 257; Number of Occupations 4; Total Number of Employees Exposed 3949; Total Number of Female Employees Exposed 408

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database
TOP