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Registry of Toxic Effects of Chemical Substances (RTECS)

Carbonic acid, diethyl ester

RTECS #

FF9800000

CAS #

105-58-8

Updated

January 1997

Molecular Weight

118.15

Molecular Formula

C5H10O3

Synonyms

DEC
Diatol
Diethylester kyseliny uhlicite (Czech)
Diethylkarbonat (Czech)
Ethoxyformic anhydride
Ethyl carbonate
Eufin
NCI-C60899

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
intraperitoneal/hamster 496 mg/kg (8D pregnant)Reproductive: Specific developmental abnormalities: Central nervous system

Reproductive: Specific developmental abnormalities: Eye, ear

Reproductive: Specific developmental abnormalities: Musculoskeletal system
CNREA8 27,1696,1967
intraperitoneal/hamster 496 mg/kg (8D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)CNREA8 27,1696,1967
intraperitoneal/hamster 1004 mg/kg (8D pregnant)Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)

Reproductive: Specific developmental abnormalities: Body wall
CNREA8 27,1696,1967

Tumorigenic Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lowest published toxic dose: 456 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors

Skin and Appendages: Tumors
BCPCA6 2,168,1959
oral/mouse lowest published toxic dose: 500 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors

Skin and Appendages: Tumors
BCPCA6 2,168,1959

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published lethal dose: 15 gm/kgFAONAU 53A,52,1974
subcutaneous/rat lethal dose (50 percent kill): 8500 mg/kgCLDND*

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code A1089; Number of Industries 3; Total Number of Facilities 415; Number of Occupations 8; Total Number of Employees Exposed 6967; Total Number of Female Employees Exposed 1022
National Occupational Hazard Survey 1974Hazard Code A1089; Number of Industries 1; Total Number of Facilities 21; Number of Occupations 2; Total Number of Employees Exposed 83

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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