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Registry of Toxic Effects of Chemical Substances (RTECS)

Carbamic acid, methyl-, 4-dimethylamino-m-tolyl ester

RTECS #

FC0175000

CAS #

2032-59-9

Updated

August 2007

Molecular Weight

208.29

Molecular Formula

C11H16N2O2

Synonyms

(4-Dimethylamino-3-methyl-phenyl)N-methyl-carbamaat (Dutch)
(4-Dimethylamino-3-methyl-phenyl)N-methyl-carbamat (German)
(4-Dimethylamino-3-methyl-phenyl)N-methyl-carbamate
(4-Dimetilamino-3-metil-fenil)-N-metil-carbammato (Italian)
4-(Dimethylamino)-3-methylphenol methyl carbamate (ester)
4-(Dimethylamino)-m-tolyl methylcarbamate
4-Dimethylamine m-cresyl methylcarbamate
4-Dimethylamino-3-cresyl methylcarbamate
A 363
Aminocarb
Aminocarbe (French)
BAY 44646
Bayer 44646
Bayer 5080
Carbamic acid, methyl-, 4-(dimethylamino)-3-methylphenyl ester
ENT 25,784
Matacil
Matacil 180D
m-Cresol, 4-(dimethylamino)-, methylcarbamate (ester)
Mitacil
N-Methylcarbamate de 4-dimethylamino 3-methyl phenyle (French)
Phenol, 4-(dimethylamino)-3-methyl-, methylcarbamate (ester) (9CI)

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysisovary/hamster5 mmol/LENMUDM 5,384,1983
mutation in microorganisms/Salmonella typhimurium5 mmol/L (-enzymatic activation step)ENMUDM 5,384,1983
sex chromosome loss and nondisjunction/Aspergillus nidulans1500 µmol/LMUREAV 178,33,1987

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 4700 µg/kgJAFCAU 15,479,1967
intraperitoneal/rat lethal dose (50 percent kill): 21 mg/kgPEMNDP 8,21,1987
oral/duck lethal dose (50 percent kill): 23 mg/kgDOEAAH 35,25,1979
oral/guinea pig lowest published lethal dose: 50 mg/kgJEENAI 60,733,1967
oral/mouse lowest published lethal dose: 94 mg/kgAECTCV 14,111,1985
oral/rat lethal dose (50 percent kill): 30 mg/kgTXAPA9 21,315,1972
oral/wild bird lethal dose (50 percent kill): 50 mg/kgTXAPA9 21,315,1972
skin/mouse lethal dose (50 percent kill): 31 mg/kgJAFCAU 15,479,1967
skin/rat lethal dose (50 percent kill): 275 mg/kgWRPCA2 9,119,1970
subcutaneous/guinea pig lowest published lethal dose: 50 mg/kgJEENAI 60,733,1967
subcutaneous/mouse lethal dose (50 percent kill): 6900 µg/kgTOIZAG 17,60,1970
unreported route/rat lethal dose (50 percent kill): 50 mg/kg30ZDA9 -,191,1971

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 44 mg/m3/2H/30D- intermittentLung, Thorax, or Respiration: Changes in lung weight

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Metabolism (intermediary): Lipids including transport
TXAPA9 82,181,1986

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWBIPHEX 58,325,2004

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESCancelledRBREV* -,159,1998
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