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Carbamic acid, dipropylthio - , S - ethyl ester

RTECS #: FA4550000

CAS #: 759-94-4


UPDATE: August 2006 MW: 189.35 MF: C9H19NOS


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Alirox
  2. Carbamothioic acid, dipropyl - , S - ethyl ester (9CI)
  3. Dipropylcarbamothioic acid S - ethyl ester
  4. EPTC
  5. Eptam
  6. Eptam 6E
  7. Ethyl N,N - di - n - propylthiolcarbamate
  8. Ethyl di - n - propylthiolcarbamate
  9. Ethyl - N,N - dipropylthiolcarbamate
  10. FDA 1541
  1. Genep EPTC
  2. N,N - Dipropylthiocarbamic acid S - ethyl ester
  3. Niptan
  4. R - 1608
  5. S - Aethyl - N,N - dipropylthiolcarbamat (German)
  6. S - Ethyldipropylthiocarbamate
  7. S - Ethyl - N,N - dipropylthiocarbamate
  8. S - Ethyl N,N - di - n - propylthiocarbamate
  9. Stauffer R 1608
  10. Torbin


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
mutation in microorganisms Escherichia coli 5 mg/L (-enzymatic activation step) GNKAA5 22,2416,1986


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
cat
lowest published lethal concentration: 400 mg/m3/4 hour Eye: Lacrimation

Behavioral: Somnolence (general depressed activity)

Gastrointestinal: Changes in structure or function of salivary glands
HYSAAV 36(1-3),196,1971
inhalation
human
lowest published toxic concentration: 135 mg/m3/90 minute Behavioral: Headache

Behavioral: Withdrawal

Gastrointestinal: Nausea or vomiting
HYSAAV 36(1-3),196,1971
inhalation
rat
lowest published lethal concentration: 200 mg/m3/4 hour Eye: Lacrimation

Behavioral: Somnolence (general depressed activity)

Gastrointestinal: Changes in structure or function of salivary glands
HYSAAV 36(1-3),196,1971
intraperitoneal
mouse
lethal dose (50 percent kill): 58 mg/kg N/R JAFCAU 25,404,1977
intravenous
mouse
lethal dose (50 percent kill): 320 mg/kg N/R CSLNX* NX#03907
oral
wild bird
lethal dose (50 percent kill): 100 mg/kg N/R TXAPA9 21,315,1972
oral
cat
lethal dose (50 percent kill): 112 mg/kg N/R HYSAAV 36(1-3),196,1971
oral
mouse
lethal dose (50 percent kill): 750 mg/kg N/R HYSAAV 36(1-3),196,1971
oral
rat
lethal dose (50 percent kill): 916 mg/kg N/R NTIS** PB82-913299
oral
rabbit
lethal dose (50 percent kill): 2,640 mg/kg N/R 85JCAE -,1020,1986
skin
rat
lethal dose (50 percent kill): 3,200 mg/kg N/R GISAAA 36(2),29,1971
skin
rabbit
lethal dose (50 percent kill): 1,460 mg/kg N/R WRPCA2 9,119,1970
unreported route
mammal (species unspecified)
lethal dose (50 percent kill): 1,660 mg/kg N/R GISAAA 45(5),29,1980
unreported route
rat
lethal dose (50 percent kill): 1,660 mg/kg N/R EQSSDX 3,618,1975


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
rat
lowest published toxic dose: 500 mg/kg/5 day- intermittent Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases

Biochemical: Metabolism (intermediary): Other proteins
CRTOEC 17,258,2004


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Supported RBREV* -,116,1998
Occupational Exposure Limit - RUSSIA short term exposure limit 2 mg/m3, JUN2003


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84803;
Number of Industries 1;
Total Number of Facilities 18;
Number of Occupations 2;
Total Number of Employees Exposed 684


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA GENETOX PROGRAM 1988, Negative: N crassa-aneuploidy
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used for control of annual grassy weeds, nutgrass, perennial weeds, etc.
On EPA IRIS database


REFERENCES:

CODEN
REFERENCE

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
CRTOEC Chemical Research in Toxicology. (American Chemical Soc., Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC 20037) V.1- 1988-
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
GNKAA5 Genetika (Moscow). For English translation, see SOGEBZ. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1965-
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued.
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued.

Used for control of annual grassy weeds, nutgrass, perennial weeds, etc.

RTECS Compound Description:
   Agricultural Chemical
   Mutagen
   Human Data

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