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Registry of Toxic Effects of Chemical Substances (RTECS)

Carbamic acid, dipropylthio-, S-ethyl ester

RTECS #

FA4550000

CAS #

759-94-4

Updated

October 2010

Molecular Weight

189.35

Molecular Formula

C9H19NOS

Synonyms

Alirox
Carbamothioic acid, dipropyl-, S-ethyl ester (9CI)
Dipropylcarbamothioic acid S-ethyl ester
Eptam
Eptam 6E
EPTC
Ethyl di-n-propylthiolcarbamate
Ethyl N,N-di-n-propylthiolcarbamate
Ethyl-N,N-dipropylthiolcarbamate
FDA 1541
Genep EPTC
N,N-Dipropylthiocarbamic acid S-ethyl ester
Niptan
R-1608
S-Aethyl-N,N-dipropylthiolcarbamat (German)
S-Ethyl N,N-di-n-propylthiocarbamate
S-Ethyldipropylthiocarbamate
S-Ethyl-N,N-dipropylthiocarbamate
Stauffer R 1608
Torbin

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Escherichia coli5 mg/L (-enzymatic activation step)GNKAA5 22,2416,1986

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/cat Lowest published lethal concentration: 400 mg/m3/4HEye: Lacrimation

Behavioral: Somnolence (general depressed activity)

Gastrointestinal: Changes in structure or function of salivary glands
HYSAAV 36(1-3),196,1971
inhalation/human lowest published toxic concentration: 135 mg/m3/90MBehavioral: Headache

Behavioral: Withdrawal

Gastrointestinal: Nausea or vomiting
HYSAAV 36(1-3),196,1971
inhalation/rat Lowest published lethal concentration: 200 mg/m3/4HEye: Lacrimation

Behavioral: Somnolence (general depressed activity)

Gastrointestinal: Changes in structure or function of salivary glands
HYSAAV 36(1-3),196,1971
intraperitoneal/mouse lethal dose (50 percent kill): 58 mg/kgJAFCAU 25,404,1977
intravenous/mouse lethal dose (50 percent kill): 320 mg/kgCSLNX* NX#03907
oral/cat lethal dose (50 percent kill): 112 mg/kgHYSAAV 36(1-3),196,1971
oral/mouse lethal dose (50 percent kill): 750 mg/kgHYSAAV 36(1-3),196,1971
oral/rabbit lethal dose (50 percent kill): 2640 mg/kg85JCAE -,1020,1986
oral/rat lethal dose (50 percent kill): 916 mg/kgNTIS** PB82-913299
oral/wild bird lethal dose (50 percent kill): 100 mg/kgTXAPA9 21,315,1972
skin/rabbit lethal dose (50 percent kill): 1460 mg/kgWRPCA2 9,119,1970
skin/rat lethal dose (50 percent kill): 3200 mg/kgGISAAA 36(2),29,1971
unreported route/mammal (species unspecified) lethal dose (50 percent kill): 1660 mg/kgGISAAA 45(5),29,1980
unreported route/rat lethal dose (50 percent kill): 1660 mg/kgEQSSDX 3,618,1975

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lowest published toxic dose: 500 mg/kg/5D- intermittentBlood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases

Biochemical: Metabolism (intermediary): Other proteins
CRTOEC 17,258,2004

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWFEREAC 75,5790,2010

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESSupportedRBREV* -,116,1998
Occupational Exposure Limit-RUSSIAshort term exposure limit 2 mg/m3, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Hazard Survey 1974Hazard Code 84803; Number of Industries 1; Total Number of Facilities 18; Number of Occupations 2; Total Number of Employees Exposed 684

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Negative: N crassa-aneuploidy
EPA TSCA Section 8(b) CHEMICAL INVENTORY
On EPA IRIS database
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