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1 - Buten - 3 - ol, 3 - methyl -

RTECS #: EM9472000

CAS #: 115-18-4


UPDATE: August 2006 MW: 86.15 MF: C5H10O


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 1,1 - Dimethylallyl alcohol
  2. 2 - Methyl - 3 - buten - 2 - ol
  3. 3 - Butyn - 2 - ol, 2 - methyl - (8CI,9CI)
  4. 3 - Methyl - 1 - buten - 3 - ol
  5. 3 - Methyl - buten - (1) - ol - (3) (German)
  1. Dimethylvinylcarbinol
  2. Dimethylvinylmethanol
  3. Methylbutenol
  4. Vinyldimethylcarbinol
  5. alpha,alpha - Dimethylallyl alcohol


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lethal concentration (50 percent kill): 2,300 mg/m3 N/R VCVGK* -,124,1984
intraperitoneal
mouse
lethal dose (50 percent kill): 800 mg/kg N/R IJSBDB 14,449,1976
intraperitoneal
rat
lethal dose (50 percent kill): 1,315 mg/kg N/R PLMEAA 48,120,1983
oral
rat
lethal dose (50 percent kill): 1,074 mg/kg N/R VCVGK* -,124,1984
subcutaneous
mouse
lethal dose (50 percent kill): 1,680 mg/kg N/R ARZNAD 5,161,1955
unreported route
mammal (species unspecified)
lethal dose (50 percent kill): 435 mg/kg N/R GISAAA 51(5),61,1986


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mammal (species unspecified)
lowest published toxic concentration: 3,000 mg/m3/4 hour/2 week- intermittent Brain and Coverings: Other degenerative changes

Blood: Changes in cell count (unspecified)
VCVGK* -,124,1994
inhalation
rat
lowest published toxic concentration: 15 mg/m3/90 day- intermittent Kidney, Ureter, and Bladder: Other changes in urine composition

Immunological Including Allergic: Decreased immune response
VCVGK* -,124,1994
oral
rat
lowest published toxic dose: 182 mg/kg/26 week- intermittent Brain and Coverings: Other degenerative changes

Liver: Other changes

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)
VCVGK* -,124,1994


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - AUSTRIA MAK 2 mg/m3 (0.6 ppm), JAN 2006


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X7945;
Number of Industries 1;
Total Number of Facilities 7;
Number of Occupations 5;
Total Number of Employees Exposed 1,557;
Total Number of Female Employees Exposed 276


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE

ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976-
PLMEAA Planta Medica. (Georg Thieme Verlag, Postfach 732, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.1- 1953-
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.

Used a flavoring, fragrance, vitamin, and drug

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