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Registry of Toxic Effects of Chemical Substances (RTECS)

1,2-Butanediol

RTECS #

EK0380000

CAS #

584-03-2

Updated

February 2003

Molecular Weight

90.14

Molecular Formula

C4H10O2

Synonyms

1,2-Butylene glycol
1,2-Dihydroxybutane

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 4192 mg/kgTXAPA9 49,385,1979
intraperitoneal/rat lowest published toxic dose: 2940 mg/kgBehavioral: AtaxiaVCVGK* -,151,1984
oral/mouse lethal dose (50 percent kill): 3720 mg/kgVCVGK* -,151,1984
oral/rat lethal dose (50 percent kill): 16 gm/kg85JCAE -,207,1986

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X7923; Number of Industries 1; Total Number of Facilities 7; Number of Occupations 1; Total Number of Employees Exposed 1822; Total Number of Female Employees Exposed 272

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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