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Registry of Toxic Effects of Chemical Substances (RTECS)

Boric acid, trimethyl ester

RTECS #

ED5600000

CAS #

121-43-7

Updated

November 2004

Molecular Weight

103.93

Molecular Formula

C3H9BO3

Synonyms

Borester O
Methyl borate
Trimethoxyborine
Trimethylester kyseliny borite (Czech)

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 500 mg moderateAJOPAA 29,1363,1946

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lowest published lethal dose: 1 gm/kg14KTAK -,693,1964
intraperitoneal/rabbit lowest published lethal dose: 1600 mg/kg14KTAK -,693,1964
intraperitoneal/rat lowest published lethal dose: 1600 mg/kg14KTAK -,693,1964
oral/mouse lethal dose (50 percent kill): 1290 mg/kg14KTAK -,693,1964
oral/rat lethal dose (50 percent kill): 6140 mg/kg14KTAK -,693,1964
skin/rabbit lethal dose (50 percent kill): 1980 µL/kgAIHAAP 23,95,1962

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 74430; Number of Industries 7; Total Number of Facilities 192; Number of Occupations 7; Total Number of Employees Exposed 4878; Total Number of Female Employees Exposed 369
National Occupational Hazard Survey 1974Hazard Code 74430; Number of Industries 3; Total Number of Facilities 50; Number of Occupations 4; Total Number of Employees Exposed 1090

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database
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