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Borate (1 - ) , tetrahydro - , sodium

RTECS #: ED3325000

CAS #: 16940-66-2

UPDATE: August 2006 MW: 37.84 MF: BH4•Na


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Borohydrure de sodium (French)
  2. Borol
  3. Hidkitex DF
  4. Sodium borohydrate
  1. Sodium hydroborate
  2. Sodium tetrahydridoborate (1 - )
  3. Sodium tetrahydroborate (1 - )


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mouse 		lowest published lethal concentration: 9 mg/m3 Eye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi 		STGNBT -,177,1999
inhalation
rat 		lethal concentration (50 percent kill): 36 mg/m3 Eye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi 		STGNBT -,177,1999
intraperitoneal
mouse 		lowest published lethal dose: 18 mg/kg N/R 14KTAK -,693,1964
intraperitoneal
rat 		lethal dose (50 percent kill): 18 mg/kg N/R AMIHAB 17,124,1958
intraperitoneal
rabbit 		lowest published lethal dose: 60 mg/kg N/R 14KTAK -,693,1964
oral
mouse 		lethal dose (50 percent kill): 50 mg/kg Eye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi 		STGNBT -,177,1999
oral
rat 		lethal dose (50 percent kill): 162 mg/kg Eye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi 		STGNBT -,177,1999
oral
rabbit 		lethal dose (50 percent kill): 50 mg/kg Eye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi 		STGNBT -,177,1999
subcutaneous
rat 		lethal dose (50 percent kill): 177 mg/kg Eye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi 		STGNBT -,177,1999
subcutaneous
rabbit 		lowest published lethal dose: 300 mg/kg Eye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi 		STGNBT -,177,1999
skin
rabbit 		lethal dose (50 percent kill): 230 mg/kg Eye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi 		STGNBT -,177,1999


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rabbit 		lowest published toxic dose: 63 mg/kg/3 week- intermittent Cardiac: Pulse rate decreased with fall in BP

Vascular: BP lowering not characterized in autonomic section

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		STGNBT -,177,1999
skin
rabbit 		lowest published toxic dose: 39 mg/kg/13 week- intermittent Cardiac: Pulse rate decreased with fall in BP

Vascular: BP lowering not characterized in autonomic section

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		STGNBT -,177,1999


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83757;
Number of Industries 5;
Total Number of Facilities 162;
Number of Occupations 4;
Total Number of Employees Exposed 977
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83757;
Number of Industries 5;
Total Number of Facilities 274;
Number of Occupations 11;
Total Number of Employees Exposed 14,408;
Total Number of Female Employees Exposed 2,344


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as inorganic reducing agent in the synthesis and purification of organic chemicals
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
14KTAK "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964
AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU.
STGNBT "Spravochnik po Toksikologii i Gigienicheskim Normativam (PDK) Potentsial'no Opasnykh Khimicheskikh Veshchestv" Kushneva, V.S., and R.B. Gorshkova, eds. 46, Zhivopisnaya St., 123182, Moscow, Russia, IzdAT 1999

Used as inorganic reducing agent in the synthesis and purification of organic chemicals

NIOSH PROFILE (BORON and ITS COMPOUNDS), SRC, 10/77

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