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Registry of Toxic Effects of Chemical Substances (RTECS)

Borate(1-), tetrahydro-, sodium

RTECS #

ED3325000

CAS #

16940-66-2

Updated

April 2012

Molecular Weight

37.84

Molecular Formula

BH4·Na

Synonyms

Borohydrure de sodium (French)
Borol
Hidkitex DF
Sodium borohydrate
Sodium hydroborate
Sodium tetrahydridoborate(1-)
Sodium tetrahydroborate(1-)

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse Lowest published lethal concentration: 9 mg/m3Eye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi
STGNBT -,177,1999
inhalation/rat lethal concentration (50 percent kill): 36 mg/m3Eye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi
STGNBT -,177,1999
intraperitoneal/mouse lowest published lethal dose: 18 mg/kg14KTAK -,693,1964
intraperitoneal/rabbit lowest published lethal dose: 60 mg/kg14KTAK -,693,1964
intraperitoneal/rat lethal dose (50 percent kill): 18 mg/kgAMIHAB 17,124,1958
oral/mouse lethal dose (50 percent kill): 50 mg/kgEye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi
STGNBT -,177,1999
oral/rabbit lethal dose (50 percent kill): 50 mg/kgEye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi
STGNBT -,177,1999
oral/rat lethal dose (50 percent kill): 162 mg/kgEye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi
STGNBT -,177,1999
skin/rabbit lethal dose (50 percent kill): 230 mg/kgEye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi
STGNBT -,177,1999
subcutaneous/rabbit lowest published lethal dose: 300 mg/kgEye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi
STGNBT -,177,1999
subcutaneous/rat lethal dose (50 percent kill): 177 mg/kgEye: Other eye effects

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi
STGNBT -,177,1999

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
skin/rabbit lowest published toxic dose: 63 mg/kg/3W- intermittentCardiac: Pulse rate decreased with fall in BP

Vascular: BP lowering not characterized in autonomic section

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
STGNBT -,177,1999
skin/rabbit lowest published toxic dose: 39 mg/kg/13W- intermittentCardiac: Pulse rate decreased with fall in BP

Vascular: BP lowering not characterized in autonomic section

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
STGNBT -,177,1999

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-FINLANDtime-weighted average 0.5 mg(B)/m3, NOV2011

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 83757; Number of Industries 5; Total Number of Facilities 274; Number of Occupations 11; Total Number of Employees Exposed 14408; Total Number of Female Employees Exposed 2344
National Occupational Hazard Survey 1974Hazard Code 83757; Number of Industries 5; Total Number of Facilities 162; Number of Occupations 4; Total Number of Employees Exposed 977

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database
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