Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Benzylamine, N,N-dimethyl-

RTECS #

DP4500000

CAS #

103-83-3

Updated

April 2012

Molecular Weight

135.23

Molecular Formula

C9H13N

Synonyms

Araldite accelerator 062
BDMA
Benzenemethanamine, N,N-dimethyl- (9CI)
Benzyl-N,N-dimethylamine
Dimethylbenzylamine
N-(Phenylmethyl)dimethylamine
N,N-Dimethylbenzenemethanamine
N,N-Dimethylbenzylamine
N-Benzyldimethylamine
Sumine 2015

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 5 mg severeDCTODJ 8,43,1985
skin /rabbit 500 mg/4H severeDCTODJ 8,43,1985

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse Lowest published lethal concentration: 1200 mg/m3/2HBehavioral: Somnolence (general depressed activity)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea
TPKVAL 5,6,1963
inhalation/mouse Lowest published lethal concentration: 1.8 gm/m3/2HTPKVAL 5,6,1963
inhalation/rat Lowest published lethal concentration: 1.8 gm/m3/2HGastrointestinal: Necrotic changes

Liver: Hepatitis (hepatocellular necrosis), zonal

Liver: Other changes
TPKVAL 5,6,1963
inhalation/rat Lowest published lethal concentration: 1200 mg/m3/2HBehavioral: Somnolence (general depressed activity)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea
TPKVAL 5,6,1963
ocular/rabbit lowest published toxic dose: 100 pphEye: Lacrimation

Eye: Conjunctiva irritation
TPKVAL 5,6,1963
oral/rat lethal dose (50 percent kill): 265 mg/kgKorCJ# 22AUG1974
skin/rabbit lethal dose (50 percent kill): 1660 mg/kgBehavioral: Tremor

Behavioral: Excitement
DCTODJ 8,43,1985

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 0.15 gm/m3/91D- intermittentLiver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Blood: Changes in spleen
TPKVAL 5,6,1963
inhalation/rat lowest published toxic concentration: 0.035 gm/m3/90D- intermittentLung, Thorax, or Respiration: Respiratory depressionTPKVAL 5,6,1963
inhalation/rat lowest published toxic concentration: 0.035 gm/m3/120D- intermittentLung, Thorax, or Respiration: DyspneaTPKVAL 5,6,1963
inhalation/rat lowest published toxic concentration: 0.035 gm/m3/0.5Y- intermittentPeripheral Nerve and Sensation: Recording from peripheral motor nerve

Lung, Thorax, or Respiration: Emphysema

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)
TPKVAL 5,6,1963
inhalation/rat lowest published toxic concentration: 0.035 gm/m3/122D- intermittentKidney, Ureter, and Bladder: Urine volume decreased or anuria

Kidney, Ureter, and Bladder: Other changes in urine composition
TPKVAL 5,6,1963

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWMUREAV 741,32,2012

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 5 mg/m3, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 83034; Number of Industries 8; Total Number of Facilities 110; Number of Occupations 8; Total Number of Employees Exposed 2150; Total Number of Female Employees Exposed 249
National Occupational Hazard Survey 1974Hazard Code 83034; Number of Industries 5; Total Number of Facilities 142; Number of Occupations 34; Total Number of Employees Exposed 23940

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
TOP