Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Benzothiazole, 2,2'-dithiobis-

RTECS #

DL4550000

CAS #

120-78-5

Updated

February 2006

Molecular Weight

332.48

Molecular Formula

C14H8N2S4

Synonyms

2,2'-Dibenzothiazyl disulfide
2,2'-Dithiobis(benzothiazole)
2-Benzothiazolyl disulfide
2-Mercaptobenzothiazole disulfide
2-Mercaptobenzothiazyl disulfide
Altax
Benzothiazole disulfide
Benzothiazolyl disulfide
Benzothiazyl disulfide
Bis(2-benzothiazyl) disulfide
Bis(benzothiazolyl) disulfide
Di-2-benzothiazolyl disulfide
Dibenzothiazolyl disulphide
Dibenzothiazyl disulfide
Dibenzoylthiazyl disulfide
Dibenzthiazyl disulfide
Dwusiarczek dwubenzotiazylu (Polish)
MBTS
MBTS rubber accelerator
Royal MBTS
Thiofide
USAF CY-5
USAF EK-5432
Vulkacit DM
Vulkacit DM/mgc

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium3333 µg/plate (+/-enzymatic activation step)EMMUEG 11(Suppl 12),1,1988
mutation in microorganismslymphocyte/mouse15 mg/L (+enzymatic activation step)ENMUDM 5,193,1983

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
parenteral/rat 400 mg/kg (4-11D pregnant)Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth)

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)
BEXBAN 93,107,1982
parenteral/rat 400 mg/kg (4-11D pregnant)Reproductive: Effects on embryo or fetus: Fetal deathBEXBAN 93,107,1982
parenteral/rat 800 mg/kg (2D male/2D prior to copulation)Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth)

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)
BEXBAN 93,107,1982
parenteral/rat 800 mg/kg (2D male/2D prior to copulation)Reproductive: Effects on embryo or fetus: Fetal deathBEXBAN 93,107,1982

Tumorigenic Data and References

Route/OrganismDoseEffectReference
oral/mouse lowest published toxic dose: 172 gm/kg/78W- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors

Blood: Tumors
NTIS** PB223-159

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 100 mg/kgNTIS** AD277-689
intraperitoneal/rat lethal dose (50 percent kill): 2600 mg/kgIPSTB3 3,93,1976
intravenous/mouse lethal dose (50 percent kill): 180 mg/kgCSLNX* NX#02251
oral/mouse lethal dose (50 percent kill): 7 gm/kgIPSTB3 3,93,1976
oral/rat lethal dose (50 percent kill): >12 gm/kgNTIS** AD755-358
skin/rabbit lethal dose (50 percent kill): >7940 mg/kgEPASR* 8EHQ-1190-0987S

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 9100 mg/kg/13W- intermittentLiver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases
KHZDAN 23,414,1980

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-RUSSIAshort term exposure limit 3 mg/m3, JUN2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 84830; Number of Industries 19; Total Number of Facilities 1533; Number of Occupations 42; Total Number of Employees Exposed 50590; Total Number of Female Employees Exposed 11091
National Occupational Hazard Survey 1974Hazard Code 84830; Number of Industries 12; Total Number of Facilities 897; Number of Occupations 28; Total Number of Employees Exposed 11180

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
TOP