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Registry of Toxic Effects of Chemical Substances (RTECS)

Benzoic acid, 2-(((((4-methoxy-6-methyl-1,3,5-triazin-2-yl)methylamino)carbonyl)amino)sulfonyl)-, methyl ester

RTECS #

DH3565000

CAS #

101200-48-0

Updated

July 2011

Molecular Weight

395.43

Molecular Formula

C15H17N5O6S

Synonyms

DPX-L 5300
Express
Express 75 DF
L 5300
Matrix
Sulfmethmeton-methyl
Tribenuron methyl

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): >5000 mg/m3/4HTOVEFN -,25,2009
oral/quail lethal dose (50 percent kill): >2250 mg/kgPEMNDP 9,840,1991
oral/rat lethal dose (50 percent kill): >5000 mg/kgTOVEFN -,25,2009
skin/rabbit lethal dose (50 percent kill): >2000 mg/kgTOVEFN -,25,2009
Tank with water/Alga lethal concentration (50 percent kill): 0.11 mg/L/14HAquatic organism effects: Growth retardationTIVIEQ 31,175,1995
Tank with water/Alga lethal concentration (50 percent kill): 0.08 mg/L/24HAquatic organism effects: Growth retardationTIVIEQ 31,175,1995

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/Dog lowest published toxic dose: 6797 mg/kg/90D- continuousNutritional and Gross Metabolic: Weight loss or decreased weight gainFEREAC 69,40909,2004
oral/Dog lowest published toxic dose: 17870.4 mg/kg/1Y- continuousBlood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
FEREAC 69,40909,2004
oral/mouse lowest published toxic dose: 15750 mg/kg/90D- continuousLiver: Other changes

Blood: Changes in spleen
FEREAC 69,40909,2004
oral/mouse lowest published toxic dose: 102562.5 mg/kg/1.5Y- continuousNutritional and Gross Metabolic: Weight loss or decreased weight gainFEREAC 69,40909,2004
oral/rat lowest published toxic dose: 6935 mg/kg/2Y- continuousBehavioral: Food intake (animal)

Liver: Changes in liver weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
FEREAC 69,40909,2004
oral/rat lowest published toxic dose: 43800 mg/kg/2Y- continuousSkin and Appendages: Other: Breast

Skin and Appendages: Tumors

Tumorigenic: Tumor types after systemic administration not seen spontaneously
FEREAC 69,40909,2004
oral/rat lowest published toxic dose: 11025 mg/kg/90D- continuousBehavioral: Food intake (animal)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
FEREAC 69,40909,2004

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWFEREAC 72,11784,2007
TOXICOLOGY REVIEWFEREAC 74,15971,2009
TOXICOLOGY REVIEWFEREAC 73,47063,2008
TOXICOLOGY REVIEWFEREAC 74,67124,2009

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESActive registrationRBREV* -,397,1998

Status in Federal Agencies

OrganizationReference
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database
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