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Registry of Toxic Effects of Chemical Substances (RTECS)

Benzene, trimethyl- (mixed isomers)

RTECS #

DC3220000

CAS #

25551-13-7

Updated

September 201

Molecular Weight

120.21

Molecular Formula

C9H12

Synonyms

Methylxylene
Trimethyl benzene (ACGIH:OSHA)
Trimethyl benzene (mixed isomers)

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 500 mg/24H mild28ZPAK -,24,1972
skin /rabbit 500 mg/24H moderate28ZPAK -,24,1972

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/rat lethal dose (50 percent kill): 8970 mg/kg28ZPAK -,24,1972

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 25 ppmDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 25 ppm (120 mg/m3)DTLVS* 3,269,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 25 ppm (123 mg/m3), JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 20 ppm (100 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 25 ppm (120 mg/m3), MAY2011
Occupational Exposure Limit-ICELANDtime-weighted average 20 ppm (100 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 25 ppm (125 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 25 ppm (125 mg/m3);short term exposure limit 35 ppm (170 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 25 ppm (123 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 20 ppm (100 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 25 ppm (123 mg/m3), JUL2005
Occupational Exposure Limit-SWEDENtime-weighted average 25 ppm (120 mg/m3);short term exposure limit 35 ppm (170 mg/m3), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 20 ppm (100 mg/m3), KZG-week 40 ppm (200 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 100 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 25 ppm (125 mg/m3), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 25 ppm (120 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 25 ppm (120 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO TRIMETHYL BENZENE-air10H time-weighted average 25 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code X1303; Number of Industries 2; Total Number of Facilities 198; Number of Occupations 2; Total Number of Employees Exposed 790; Total Number of Female Employees Exposed 365

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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