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Registry of Toxic Effects of Chemical Substances (RTECS)

Benzenesulfonic acid, 5-chloro-2-((2-hydroxy-1-naphthalenyl)azo)-4-methyl-, barium salt

RTECS #

DB5500000

CAS #

5160-02-1; 12237-52-4; 12238-39-0; 12238-41-4; 12238-43-6; 24777-23-9; 52627-68-6; 68894-03-1

Updated

November 2009

Molecular Weight

444.49

Molecular Formula

C17H12ClN2O4S·1/2Ba

Synonyms

1-(4-Chloro-o-sulfo-5-tolylazo)-2-naphthol, barium salt
1-(4-Chloro-o-sulpho-5-tolylazo)-2-naphthol, barium salt
1860 Red
5-Chloro-2-((2-hydroxy-1-naphthalenyl)azo)-4-methylbenzenesulfonic acid, barium salt (2:1)
5-Chloro-2-((2-hydroxy-1-naphthalenyl)azo)-4-methylbenzenesulphonic acid, barium salt
5-Chloro-2-((2-hydroxy-1-naphthyl)azo)-p-toluenesulfonic acid, barium salt
Astro Orange
Atomic Red
Brilliant Red
Brilliant Scarlet CA
Brilliant Scarlet CBA
Brilliant Scarlet CTA
Brilliant Toner Z
Bronze Red 16913 Yellowish
Bronze Red RO
Bronze Scarlet
Bronze Scarlet C
Bronze Scarlet CA
Bronze Scarlet CBA
Bronze Scarlet CT
Bronze Scarlet CTA
Bronze Scarlet Toner
C.I. 15585:1
C.I. Pigment Red 53, barium salt
C.I. Pigment Red 53:1
Carnation Red
Cosmetic Coral Red KO Bluish
Cosmetic DVR
Cosmetic Pigment Yellow Red DVR
D & C Red No. 9
D and C Red No. 9
Dainichi Lake Red C
Desert Red
Duplex Red Lake C20-5925
Eljon Lake Red C
Hamilton Red
Helio Red Toner LCLL
Irgalite Red CBN
Irgalite Red CBR
Irgalite Red CBT
Irgalite Red MBC
Isol Lake Red LCS 12527
Isol Red LCR 2517
Lake Red 1520
Lake Red C
Lake Red C 18287
Lake Red C 21245
Lake Red C 27200
Lake Red C 27217
Lake Red C 27218
Lake Red C Barium Toner
Lake Red C Toner 8195
Lake Red C Toner 8366
Lake Red CC
Lake Red CCT
Lake Red CR
Lake Red CRLC-232 (barium)
Lake Red GB barium salt
Lake Red RRG
Lake Red Toner C
Lake Red Toner LCLL
Latexol Scarlet R
Latexol Scarlet R Solupowder
Ld Rubber Red 16913
Lutetia Red CLN
Lutetia Red CLN-ST
Microtex Lake Red CR
Mohican Red A-8008
NCI-C53792
No.3 Conc. Bronze Scarlet
No.3 Conc. Scarlet
Paridine Red LCL
Pigment Lake Red BFC
Pigment Lake Red CD
Pigment Lake Red LC
Pigment Red 53:1
Pigment Red CD
Potomac Red
Recolite Red Lake C
Recolite Red Lake CR
Red 16913H
Red 1860
Red For Lake C
Red For Lake C Toner RA-5190
Red For Lake Toner RA-5190
Red Lake C
Red Lake C Toner
Red Lake C Toner 20-5650
Red Lake C Toner RA-5190
Red Lake CM 20-5650
Red Lake CR-1
Red Lake R-91
Red Scarlet
Red Toner Z
Rubber Red 16913R
Sanyo Lake Red C
Scarlet Toner Y
Segnale Red LC
Segnale Red LCG
Segnale Red LCL
Sico Lake Red 2L
Superol Red C RT-265
Symuler Lake Red C
Termosolido Red LCG
Texan Red Toner D
Toner Lake Red C
Transparent Bronze Scarlet
Vulcafix Scarlet R
Vulcafix Scarlet R-D masse
Vulcafor Red 2R
Vulcan Red LC
Vulcol Fast Red L
Wayne Red X-2486

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium1 mg/plate (+enzymatic activation step)SCIEAS 236,933,1987
mutation in microorganisms/Salmonella typhimurium100 mg/L/2H (+enzymatic activation step)EMMUEG 44,329,2004

Tumorigenic Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 130 gm/kg/2Y- continuousTumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors

Blood: Tumors
NTPTR* NTP-TR-225,1982
oral/rat toxic dose: 109 gm/kg/2Y- continuousTumorigenic: Neoplastic by RTECS criteria

Blood: Tumors
FCTOD7 25,619,1987
oral/rat lowest published toxic dose: 16380 mg/kg/13W- continuousTumorigenic: Neoplastic by RTECS criteria

Blood: Changes in spleen

Blood: Other changes
NTIS** PB82-229592
oral/rat lowest published toxic dose: 27300 mg/kg/13W- continuousTumorigenic: Neoplastic by RTECS criteria

Blood: Changes in spleen

Blood: Other changes
NTIS** PB82-229592
oral/rat lowest published toxic dose: 129780 mg/kg/103W- continuousTumorigenic: Carcinogenic by RTECS criteria

Blood: Tumors
NTIS** PB82-229592
oral/rat lowest published toxic dose: 108150 mg/kg/103W- continuousTumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors
NTIS** PB82-229592

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
oral/mouse lethal dose (50 percent kill): >10000 mg/kgHPV152 -,-,2006
oral/rat lethal dose (50 percent kill): >10000 mg/kgHPV152 -,-,2006

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/mouse lowest published toxic dose: 21 gm/kg/14D- continuousRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldNTPTR* NTP-TR-225,1982
oral/mouse lowest published toxic dose: 87600 mg/kg/2Y- continuousBlood: Changes in erythrocyte (RBC) countNTIS** OTS0543935
oral/rat lowest published toxic dose: 43260 mg/kg/103W- continuousBlood: Leukemia

Reproductive: Tumorigenic effects: Testicular tumors

Tumorigenic: Active as anti-cancer agent
NTIS** PB82-229592
oral/rat lowest published toxic dose: 36050 mg/kg/103W- continuousBlood: Leukemia

Tumorigenic: Active as anti-cancer agent
NTIS** PB82-229592
oral/rat lowest published toxic dose: 13650 mg/kg/91D- intermittentLiver: Other changes

Blood: Normocytic anemia

Blood: Changes in spleen
HPV152 -,-,2006
oral/rat lowest published toxic dose: 27300 mg/kg/91D- continuousLiver: Other changes

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
NTPTR* NTP-TR-225,1982
oral/rat lowest published toxic dose: 546 gm/kg/2Y- continuousEndocrine: Changes in spleen weightTXAPA9 4,200,1962

Reviews

OrganizationStandardReference
International Agency for Research on Cancer (IARC)Cancer Review:Animal Limited EvidenceIMEMDT 57,203,1993
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 8,107,1975
International Agency for Research on Cancer (IARC)Cancer Review:Human No Adequate DataIMEMDT 8,107,1975
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 57,203,1993
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMEMDT 57,203,1993
TOXICOLOGY REVIEWMUREAV 543,201,2003
TOXICOLOGY REVIEWMUREAV 584,1,2005

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-MEXICOtime-weighted average 0.5 mg(Ba)/m3, 2004
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.5 mg(Ba)/m3, 2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code M3849; Number of Industries 43; Total Number of Facilities 8245; Number of Occupations 49; Total Number of Employees Exposed 122313; Total Number of Female Employees Exposed 23095
National Occupational Hazard Survey 1974Hazard Code M3849; Number of Industries 15; Total Number of Facilities 1160; Number of Occupations 21; Total Number of Employees Exposed 14370

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NCI Carcinogenesis Studies (feed);equivocal evidence:rat
NTP Carcinogenesis Bioassay (feed);clear evidence:rat NTPTR* NTP-TR-225,1982
NTP Carcinogenesis Bioassay (feed);no evidence:mouse NTPTR* NTP-TR-225,1982
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