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Benzenesulfonic acid

RTECS #: DB4200000

CAS #: 98-11-3

UPDATE: May 2006 MW: 158.18 MF: C6H6O3S


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. 17 - 120A
  2. Benzenemonosulfonic acid
  3. Benzene sulphonic acid
  1. Besylic acid
  2. Kyselina benzensulfonova (Czech)
  3. Phenylsulfonic acid


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		250 µg/24 hour severe 85JCAE -,1053,1986
skin
human 		0.2% mild TOXID9 66,167,2002
skin
rabbit 		100 µg/24 hour open irritation test mild AIHAAP 23,95,1962
skin
rabbit 		2 mg/24 hour severe 85JCAE -,1053,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
wild bird 		lethal dose (50 percent kill): 75 mg/kg N/R TXAPA9 21,315,1972
oral
rat 		lethal dose (50 percent kill): 890 µL/kg N/R AIHAAP 23,95,1962
skin
cat 		lowest published lethal dose: 10 gm/kg Behavioral: Tremor

Behavioral: Muscle weakness

Gastrointestinal: Changes in structure or function of salivary glands 		JPETAB 84,358,1945


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X7434;
Number of Industries 2;
Total Number of Facilities 28;
Number of Occupations 2;
Total Number of Employees Exposed 3,164


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as intermediate in chemical syntheses
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

Used as intermediate in chemical syntheses

NIOSH PROFILE (SULFONIC ACIDS AND SALTS, ARYL), SRC, 12/79

RTECS Compound Description:
   Human Data
   Primary Irritant

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